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How does taking too many tyelonel affect your liver, and does the damage show up right away?

2006-11-09 14:12:51 · 6 answers · asked by Kelly 2 in Health Other - Health

6 answers

The Tylenol that you take is processed and eliminate from your body by the liver. The liver uses an enzyme to break down the Tylenol and the Tylenol's breakdown products. Now, one of the breakdown products of Tylenol is very, very toxic to the liver, and if you overwhelm the liver's system by taking too much Tylenol, you can develop Tylenol toxicity.

There are two forms of Tylenol toxicity - one is chronic, where someone has taken too much Tylenol over a period of time - an example is someone who takes more than the recommended dose for several days for pain control. The second type is acute toxicity - where someone attempts to suicide via Tylenol overdose.

The damage usually takes a little while to show up in an acute ingestion - someone who just took 100 pills can come to the ER a few hours later, say they took 100 pills, but their liver enzymes will be fine. People usually develop problems about a day or 2 after ingestion.

What happens first is that your liver enzymes rise - indicating damage to the actual cells that make up your liver. If there is enough damage, you go into liver failure. As a result of liver failure, you get a build up of waste products in your blood, and all your clotting factors get messed up - so you have an increased likelihood of bleeding, among other things.

We treat Tylenol overdose with something called NAC - N-acetylcysteine - which helps to prevent that toxic byproduct of Tylenol breakdown from building up in the liver. The only other thing you can really do is supportive care.

Hope that answers your question.

2006-11-09 14:30:31 · answer #1 · answered by Wondering 3 · 0 0

It causes an increase in liver enzymes, swelling of the liver and too much causes permanent liver damage. Most of the people who try to commit suicide with Tylenol pm fail and wind up with permanent liver damage. The affect on the liver is almost immediate but with the correct dosage of Tylenol it is insignificant unless there are already problems with the liver or you are taking other medications or drinking which affects the liver.

2006-11-09 14:16:55 · answer #2 · answered by Anonymous · 0 0

* Acetaminophen is a very safe drug when taken as directed, even for people with liver disease. Nevertheless, every drug carries risks.

* Liver damage from acetaminophen, which can be severe, can result either from an overdose or from regular doses that are taken while drinking alcohol.

* Most cases of acetaminophen-induced liver injury are caused by an intentional or suicidal overdose.

* Unintentional or accidental overdose of acetaminophen can usually be avoided with care and attention to the dosing.

* Physicians can estimate a patient's probability of developing liver injury based on the timing of the overdose and the blood level of the drug.

* In patients with acetaminophen liver damage, the usual clinical sequence is nausea and vomiting for the first 12-24 hours, then the patient seems well for the next 12-24 hours, after which abnormal liver blood tests develop.

* An antidote, N-acetyl cystiene, is available and should be given to the patient as soon as possible, preferably within 16 hours after the acetaminophen was taken.

For more info, read the article that I've posted a link to: http://www.medicinenet.com/tylenol_liver_damage/article.htm

2006-11-09 14:17:57 · answer #3 · answered by rita_alabama 6 · 0 0

well from my understanding it is cause the tylenol doesnt disolve in your liver like most medications and it takes time to cause damage if u were to take alot at a time or they say if u drink alot of alcohol not to take tylenol for that reason but if for just a headache or something i bet it wont cause no damage.

2006-11-09 14:23:25 · answer #4 · answered by carmen_dyer2000 2 · 0 0

The damage could take days or years to show up depending on how much you take and how often you do it.

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2016-05-16 11:41:39 · answer #6 · answered by Anonymous · 0 0

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