Willbetrun XL?

Question

I started taking willbetrub xl about 2 weeks ago. Ive noticed a tremendous drop in weight. For the first 1 week the medicince was working perfectly then it crashed for some reason and now feel more depressed then i was before i got on the medication. Is this normal?????

Answer 1

Anti-depressants can take longer than 2 weeks to work. I can't imagine it could work in the first week.

Is it possible that you were helping yourself out of the depression and trying to resume a full life and then crashed? That often happens because we start to feel better and go for it and then regress further than where we started.

My doctor booked my first follow-up for 3 weeks after started meds.

Answer 2

I gained 30 lbs on Effexor XL and it was not my normal weight. I was at like 160 and it was from the pill. I worked out like a fiend, dieted and coould not lose a lb. I went off of it and started taking Wellbutrin XL and lost it all and then a few lbs to about 128. But that was in a years time. The Wellbutrin XL to me makes food not takes as good and I got full fast. I have hardly had any side effects from an antidepressant and this works ok-I am not depressed, I have anxiety disorder and panic.I think to get the full effect you have to take it for a month or two. I'd call the doctor if you are worried.

Answer 3

This is a good question amongst antidpressant meds. I'm not a Dr. so what I'm about to say is purely speculative and I would discuss this issue with your Dr. as soon as possible if I were you.

When treating depression, there are 3 different neurotransmitters that come in to play, serotonine, dopamine and neuropenephrine. The challenge in treating depression is finding out which of the three isn't sticking around long enough, therefore, there are two more selective types of antidpepressants on the market. These are reuptake inhibitors which regulate the juices in your head, in areas where you may need them to be more readily available, dicipating that hole of depression that you fall into, which really sucks.

1. SSRI's - Selective serotonin reuptake inhibitors, such as Paxil, Zoloft and the more popular Lexapro/Celexa; which target serotonin
2. MRI - Multiple reuptake inhibitors, such as Wellbutrin, Effexor and Cymbalta, which target, Neuropinephrine and Dopamine

Based on what you described you may be experiencing one of the following;

1. Reuptake failure - It's possible with all reuptake inhibitors that they just stop working at any point of time. You haven't been on it that long, but it's still possible that Wellbutrin just won't work for you, which would explain the increased depression

2. According to the patient information sheets, it takes 8 days to reach the theraputic level and about 2 weeks before it kicks in full effect. With all antidepressants, it's good to give it a full month before you give up on it. However, you may have experienced the placebo effect for the first week, where it may kick in in another week. However, if you are desperate to get off your depression, ask your Dr. to give you something else.

As for the typical side effects, which are, Agitation, anxiety, insomnia, weight loss (bupropion is undergoing trials as a weight loss medication), headache, dry mouth, nausea, constipation, dizziness. Most of these are transitory, but the weight loss, agitation and insomnia tend to stick around.

If you're uncomforable with the weight loss, you may want to entertain taking other MRI's, however, I would stay away from Effexor, as it the hardest to quit and has the harshest discontinuation syndrome.

I hope this helps and good luck!

Answer 4

Wellbutrin is the correct spelling. In Wellbutrin's proflle weight loss is a probability. Also never take any time or extended release formulars. W. comes in a standard formular. If it was working for you take 75- 100 mg (standard formular) twice daily. Morning after breakfast and early afternoon after lunch. It can keep you up at night if you take it too late in the day. Also W. has a positive profile in regards to one's sexual health where all the other anti-depresseant have a negative profile + weight gain. W. has a very similar profile as Cocaine. There are also many good herbal formulars (Ayurveda and Chinese) which are better than W.

Answer 5

no. Contact your prescribing doctor and your therapist (if they are seperate people) immediately. Leave messages on their services and ask for appointments as soon as possible. YOu need to try a different anti-depressant, but your body can still have withdrawels if you simply stop taking it. Since you have had a poor reaction, simpl stopping taking any more could make things worse. Again, contact your providers, tell them the meds are not working and you have increased depression.

Answer 6

no it isn't and since it was probably meant to stabilize your mental state then i recommend that you call your doctor and tell them about what side effects you are experiencing. it is normal to have to change anti depressants though to find the one that works the best for you and your body chemistry.