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where is protease find in body?is it in stomach?where do the proteins we eat get broken down?

2006-11-03 09:36:58 · 5 answers · asked by Anonymous in Science & Mathematics Medicine

5 answers

Proteases (proteinases, peptidases, or proteolytic enzymes) are enzymes that break peptide bonds between amino acids of proteins. The process is called proteolytic cleavage, a common mechanism of activation or inactivation of enzymes, especially those involved in blood coagulation or digestion. They use a molecule of water for this and are thus classified as hydrolases.

Digestion typically begins in the stomach when pepsinogen is converted to pepsin by the action of hydrochloric acid, and continued by trypsin and chymotrypsin in the intestine. The amino acids and their derivatives into which dietary protein is degraded are then absorbed by the gastrointestinal tract. The absorption rates of individual amino acids are highly dependent on the protein source; for example, the digestibilities of many amino acids in humans differ between soy and milk proteins[2] and between individual milk proteins, beta-lactoglobulin and casein.[3] For milk proteins, about 50% of the ingested protein is absorbed between the stomach and the jejunum and 90% is absorbed by the time the digested food reaches the ileum.[4]

2006-11-03 12:57:29 · answer #1 · answered by Anonymous · 0 0

Enzymes that degrade ( hydrolyze ) other proteins are called proteases. There are four general classes of proteases distinguiished by the type of amino acid at the active site of the protease enzyme or the need for an essential metal, and their effective pH ranges. Aspartyl proteases, EX. PEPSIN pH range ~ 2- 4 Cysteine proteases EX PAPAIN pH range -- 4.5 -6.5 Serine Proteases EX TRYPSIN pH range -- 7- 9 Metalloproteases EX collagenase pH range --6-8 contain a metal such as zinc for activity

2016-03-28 05:56:40 · answer #2 · answered by ? 4 · 0 0

The proteins are broken down in the stomach and small intestines. The protease in the stomach is pepsin the small intestine proteolytic enzymes are are formed in the pancreas and are trypsin and chymotypsin.

2006-11-03 10:14:49 · answer #3 · answered by ocgcnr 1 · 2 0

Almost every cell contain protease enzymes.
There's others protease enzymes other than digestive enzymes.(e.g, some include in hormone synthesis in endocrine cells)
For protein digestion,it begins in stomach ,where it it denatured by hydrochloric acid and digested by proteolytic enzymes of stomach.And there's proteolytic enzymes produced by pancreas and small intestine too.

2006-11-03 14:06:05 · answer #4 · answered by elle 2 · 0 0

I think it's found in the small intestine, the protein is broken down and it is then small enough to pass through the thin walls on either side of the intestine. Of course, I don't know for sure that this is correct, you may have to look on the internet.

2006-11-03 09:42:45 · answer #5 · answered by anonymouse 3 · 0 0

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