what is inositol? is it harmful?

Answer 1

Inositol is part of the vitamin B-complex. It is required for proper formation of cell membranes.

Inositol affects nerve transmission and helps in transporting fats within the body. Inositol differs from inositol hexaniacinate, a form of vitamin B3.

Where is it found?
Nuts, beans, wheat and wheat bran, cantaloupe, and oranges are excellent sources of inositol. Most dietary inositol is in the form of phytate.

Are there any side effects or interactions?
Toxicity has not been reported, although people with chronic renal failure show elevated levels and should not take inositol, except under medical supervision.

Large amounts of phytate, the common dietary form of inositol, reduce the absorption of calcium, iron, and zinc. However, supplemental inositol does not have this effect.

One review article suggested that inositol may stimulate uterine contractions.5 While no research has demonstrated that inositol actually has this effect, women who are or could become pregnant should consult a doctor before taking inositol.

Are there any drug interactions?
Certain medicines may interact with inositol. Refer to drug interactions for a list of those medicines.

Who is likely to be deficient?
Clear deficiency of inositol has not been reported, although people with diabetes have increased excretion and may benefit from inositol supplementation.

How much is usually taken?
Most people do not need to take inositol. In addition, the small amounts commonly found in multivitamin supplements are probably unnecessary and ineffective. Doctors sometimes suggest 500 mg twice per day. For depression, anxiety, and obsessive-compulsive disorder, 12–18 grams per day has been shown to be effective in double-blind trials.

Answer 2

Once you rule out any medical condition, give family and Cognitive-Behavioral Therapy a chance before introducing any natural or manufactured medications. Also, any meds or supplements should only be prescribed by a licensed physician. Moreover, OCD in young males is not usually diagnosed (nor should it be) until the child is at least 6 years of age, anyway. I suggest it is better to rule out any organic causes for the OCD/Anxiety first, then proceed with talk/play therapy to determine if environmental/psychological factors are contributing to the problem. Consider medication as a last resort. Medications can be very helpful, but it is always a sound practice to start with less intrusive measures, first. Later, it may be determined that the combination of meds and therapy are in the child's best interest. Take Care.

Answer 3

Inositol Powder Cutting Agent

Answer 4

Inositol, or cis-1,2,3,5-trans-4,6-cyclohexanehexol, is a cyclic polyalcohol that plays an important role as a second messenger in a cell, in the form of inositol phosphates. It is found in many foods, particularly in cereals with high bran content.

It is classified as a member of the vitamin B complex, though it is not considered a vitamin itself because it can be synthesized by the human body.

Structure

The chemical formula of inositol is C6H12O6. In its most stable geometry, the inositol ring is in the chair conformation. There are nine stereoisomers, all of which may be referred to as inositol; however, the most common in nature has a structure in which the 1st, 3rd, 4th, 5th and 6th hydroxyls are positioned equatorially to the plane of the ring, while the 2nd hydroxyl group is positioned axially to the plane of the ring.

Synthesis

Inositol is synthesized from glucose-6-phosphate (G6P) in two steps. First, G6P is isomerized by INYNA1 to myo-inositol 1-phosphate, which is then dephosphorylated by IMPA1 to yield inositol.

Answer 5

Inositol, or cis-1,2,3,5-trans-4,6-cyclohexanehexol, is a cyclic polyalcohol that plays an important role as a second messenger in a cell, in the form of inositol phosphates. It is found in many foods, particularly in cereals with high bran content.

It is classified as a member of the vitamin B complex, though it is not considered a vitamin itself because it can be synthesized by the human body.

[edit] Structure
The chemical formula of inositol is C6H12O6. In its most stable geometry, the inositol ring is in the chair conformation. There are nine stereoisomers, all of which may be referred to as inositol; however, the most common in nature has a structure in which the 1st, 3rd, 4th, 5th and 6th hydroxyls are positioned equatorially to the plane of the ring, while the 2nd hydroxyl group is positioned axially to the plane of the ring.


[edit] Synthesis
Inositol is synthesized from glucose-6-phosphate (G6P) in two steps. First, G6P is isomerized by INYNA1 to myo-inositol 1-phosphate, which is then dephosphorylated by IMPA1 to yield inositol.


[edit] Function
Inositol is inolved in many biological processes, including:

cytoskeleton assembly
nerve guidance (Epsin)
intracellular calcium (Ca2+) concentration control
cell membrane potential maintenance
serotonin activity modulation
breakdown of fats and reducing blood cholesterol[citation needed]
gene expression (Wu 2003 and OShea 2003, both in Science)

[edit] Clinical implications
Some preliminary results of studies on inositol supplements show promising results for people suffering from problems such as bulimia, panic disorder and bipolar depression.

Inositol has been found in double-blind studies to be an effective treatment for obsessive-compulsive disorder (OCD). It is equal in effectiveness to SSRIs and is virtually free from side effects.[2][3][4]


[edit] Illicit uses
Inositol powder can be used in small proportions as a cutting agent for cocaine HCL or methamphetamine (crystal meth). It has an almost identical appearance when in powder form and portrays similar qualities when heated. This, in addition to the fact that it adds almost no discernable taste or feel to either drug regardless the method of use, makes it an ideal cutting agent. Cutting either drug at any point in the distribution increases volume of the street product and increases dealer profits. However, at higher cut levels the inositol becomes somewhat noticeable in that the quality of the product is obviously diminished.

Answer 6

I found this on the internet:
Therapeutic Uses
Some but not all studies suggest that high-dose inositol may be useful for depression.1–4

Inositol has also been studied for bipolar disorder,5panic disorder,6,7bulimia,8 and obsessive-compulsive disorder,9,10 but the evidence remains far from conclusive. Other potential uses include Alzheimer's disease11 and attention deficit disorder.12

According to one substantial double-blind study, inositol may help improve various symptoms of polycystic ovary syndrome, including infertility and weight gain. 31

Another very small double-blind study found that inositol supplements could help reduce symptoms of psoriasis triggered or made worse by use of the drug lithium.32

A small double-blind study failed to find inositol helpful for premenstrual dysphoric disorder, a severe form of PMS.30

Inositol is sometimes proposed as a treatment for diabetic neuropathy, but there have been no double-blind, placebo-controlled studies on this subject, and two uncontrolled studies had mixed results.13,14

Inositol has also been investigated for potential cancer-preventive properties.15–22


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What Is the Scientific Evidence for Inositol?
Depression
Small double-blind studies have found inositol helpful for depression.23,24 In one such trial, 28 depressed individuals were given a daily dose of 12 g of inositol for 4 weeks.25 By the fourth week, the group receiving inositol showed significant improvement compared to the placebo group.

However, a double-blind study of 42 people with severe depression that was not responding to standard antidepressant treatment found no improvement when inositol was added.26

Panic Disorder
People with panic disorder frequently develop panic attacks, often with no warning. The racing heartbeat, chest pressure, sweating, and other physical symptoms can be so intense that they are mistaken for a heart attack. A small double-blind study (21 participants) found that people given 12 g of inositol daily had fewer and less severe panic attacks as compared to the placebo group.27

A double-blind, crossover study of 20 individuals compared inositol to the antidepressant drug fluvoxamine (Luvox), a medication related to Prozac.28 The results over 4 weeks of treatment showed that the supplement was at least as effective as the drug.

Bipolar Disorder
In a 6-week, double-blind study, 24 individuals with bipolar disorder received either placebo or inositol (2 g three times daily for a week, then increased to 4 g three times daily) in addition to their regular medical treatment.5 The results of this small study failed to show statistically significant benefits; however, promising trends were seen that suggest a larger study is warranted.

Hope it helps!

Answer 7

This Site Might Help You.

RE:
what is inositol? is it harmful?

Answer 8

It could lead to nausea, an upset stomach, diarrhea, dizziness, headaches, insomnia and red or itchy skin.

Here is a good video on the dangers of inositol.

https://www.youtube.com/watch?v=TQwGd5FICG8

Answer 9

Hello, I did not find it on the meds list but maybe you have a spelling typo. Here is the website for medical info including medications. good luck

http://www.medicinenet.com/medications/article.htm

Answer 10

What Is Inositol