methanol acute toxicity differential diagnosis?

Question

toxicology science

Answer 1

As and when you can learn how to phrase a question properly people might answer with something helpful.

Are you wanting an example, a definition, someone who wrote an article about it? LD50 figures for comparison?

And for the benefit of the other chap, methane and methanol are a bit different from each other. Methanol is gobsmackingly toxic and breaks down into such delightful things as formic acid and formaldehyde (embalming fluid) inside the body.

Answer 2

A toxicology lab equipped with a gas chromatograph and set up to do a volatile alcohol screen can differentiate very quickly between methanol, ethanol, acetone and isopropanol. The use of enzymatic analysis via alcohol-dehydrogenase will not differentiate between the parent compounds.The gas chromatographic analysis produces separate peaks for identification with known standards. This test can be set up to yield quantitative results and can be done on any body fluid. Whole blood or serum is usually used. Methanol ingestion is extremely dangerous as methanol selectively attacks the optic nerve and serious impairment and blindness can occur.

Answer 3

In a clinical setting patient history would be the primary method.

In a toxicology laboratory screening for the metabolic breadown products would the the approach. The enzyme alcohol dehydrogenase will convert methanol to formaldehyde which is detectable on assay.

Answer 4

Methane is no toxic at the level in the open atmosphere. It is much lighter than air and it escapes quickly. If u breath it u might get happy like Alchol. It also has nothing to do with global warming go measure it.

Answer 5

Absolutely.