tell me about this disease?

Question

Tell me about the sickle cell disease. tell me all that u know about. and please let it be an intelligent answer!

Answer 1

"Sickle cell disease is an inherited blood disorder that affects red blood cells. People with sickle cell disease have red blood cells that contain mostly hemoglobin* S, an abnormal type of hemoglobin. Sometimes these red blood cells become sickle-shaped (crescent shaped) and have difficulty passing through small blood vessels.

When sickle-shaped cells block small blood vessels, less blood can reach that part of the body. Tissue that does not receive a normal blood flow eventually becomes damaged. This is what causes the complications of sickle cell disease. There is currently no universal cure for sickle cell disease.

Hemoglobin – is the main substance of the red blood cell. It helps red blood cells carry oxygen from the air in our lungs to all parts of the body. Normal red blood cells contain hemoglobin A. Hemoglobin S and hemoglobin C are abnormal types of hemoglobin. Normal red blood cells are soft and round and can squeeze through tiny blood tubes (vessels). Normally, red blood cells live for about 120 days before new ones replace them.

People with sickle cell conditions make a different form of hemoglobin A called hemoglobin S (S stands for sickle). Red blood cells containing mostly hemoglobin S do not live as long as normal red blood cells (normally about 16 days). They also become stiff, distorted in shape and have difficulty passing through the body’s small blood vessels. When sickle-shaped cells block small blood vessels, less blood can reach that part of the body. Tissue that does not receive a normal blood flow eventually becomes damaged. This is what causes the complications of sickle cell disease."

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Answer 2

Sickle cell disease is a genetically inherited recesive disease. That means that both parents must have the gene for the children to inherit it. There is a theory that states that it is a mutation that should protect the patient against malaria, destroying the RBCs before the plasmodium begins to reproduce.
There is the trait, and there is the disease. It is said that approximately 7% of Africanamericans have the trait. This means that they don't suffer the disease.
The homozygotes ( have genes from both parents ) show in the blood 90% of hemoglobin S and 10% of fetal hemoglobin. They will suffer acute vaso oclusive episodes with chest pain, fever, jaundice, pallor, hemolytic crises, where the RBCs are destroyed, creating a reduction in hemoglobin ( anemia ).
When the RBCs are in an environment of decreased oxygen, or hemoconcentration, they take the shape of a half moon, or sickle, but in this condition they become fragile and are destroyed, creating an obstruction in the blood vessels. This will produce thromboses and multiple infarctions
This crises may be precipitated by infection, dehydration, or hypoxia. The patients suffer loss of spleen because of multiple infarcts. Diagnosis is made with a peripheral blood smear, CBC, and hemoglobin electrophoresis. Treatment: hydration, hydroxyurea, oxygen, analgesis

Answer 3

Sickle cell disease is an inherited blood disorder that affects red

blood cells. The red blood cells (donut shaped sells) become

sickle-shaped (crescent shaped) and makes it tough to go

other red cells. The sickle cells will block the path and your

tissue will not have a normal blood flow and becomes damaged.

The disease is inherited from parents like the way you inherit

your other traits. Sadly, there is no cure for this desease.

~Kitten~

Answer 4

Usually is a disease of folks that live around the Mediterranean and the African American folks. the Red Blood Cells in the blood system are not round shaped, but are 'moon' shaped like that on the flag of the muslim faith ie Saudi Arabia has a cresent moon on their flag. Don't know how else to explain the shape. These red blood cells do not carry as much oxygen from the lungs to the rest of the body like the normal red blood cells do, therefore these folks need regular blood transfusions, so that donar blood can do the job for them.

Answer 5

It is a hereditary chronic form of anemia in which abnormal sickle, or crescent shaped cells are present in the blood. It is cause by a lack of hemoglobin S in the red blood cells..