Why don't the anti-a and anti-b antibodies in type O blood attack the A and B antigens in A,B or AB blood when

Question

they are transfused.

Answer 1

depends.

if they only transfused the erythrocytes, ofcourse they won`t.

but if they transfer the blood plasma, the anti a & anti b DO ATTACK the antigens, but the amount of those aglutinin are small (few) , so it isn`t a big deal/

Answer 2

They do attack the A and B antigens, that is why type O people can only receive blood from type O donors. If someone is type O their blood can be given to anybody else, because it lacks the A and B antigens. So, since type O blood has no atigenic determinants it can be used for any transfusion. Also, it cannot receive any bloods with A or B antigens, because it has both the anit-A and anti-B antibodies.

Answer 3

They do. If a person with type O blood receives a transfusion of type A, B, or AB blood, his or her body will reject the transfusion and will attack the new blood cells. But when type O blood is transfused into a person with A, B, or AB blood, it's okay, because only the type O blood itself is transfused, not the anti-A and anti-B antibodies from the donor's immune system.

Answer 4

The blood is centrifuged, causing the RBC's to collect at the bottom, and then they are washed to remove nearly all antibody. Even if some antibodies did get into your system, they would be too few to cause a reaction, and there would be no memory cells for them to trigger to create a larger reaction. This is why we can't just inject people with antibodies to diseases they might have, it wouldn't be able to mount a strong enough response. Read up on t-cell memory if you want more info, but it's a good question

Answer 5

The Anti-A and Anti-B of a type O are present in small amounts at birth. The amount grows and is at a ligh titer, level, by 6 weks or so of age. It is genetic. They are large, naturally occuring, antibodies and very efficient. These antibodies are too large to cross the plascental barrier so they don't hurt an A or B fetus of an O mother. On occasion a mother may develop a small, IgG Anti A or Anti B, after being sensitized from an A or B fetus. Then later babies could have hemolytic disease.

In blood banks we give ***/Rh specific RBC products. One unit of *** incompatible red blood cells could quickly kill a recipient. Platelets and plasma products are generally small volumes and are given *** compatible.

Is this the answer to your question?

Answer 6

I think you are referring to O being transfused to A,B or AB patients. The antibodies are found in the plasma, and the plasma is removed from the donated blood. Plasma is the straw colored fluid that red cells float in. It contains antibodies, nutrients and clotting factors. Blood centers remove the plasma so that it can be frozen and transfused as a separate component. Good question!

Answer 7

Most transfusions today are as blood products, not whole blood. Blood is spun down into it's components: red blood cells, plasma, and the Buffy coat which is all the other cells. When someone needs a transfusion because his red cell count is too low, he is given pRBCs or packed red blood cells. This excludes antibodies.

Answer 8

It's not whether the donor has antibodies in his or her blood; they quickly become diluted in the recipient's blood. It is whether the recipient's immune system will start to make massive amounts of antibody against the donor's RBCs

Answer 9

Like the guy above said THEY DO.

I'll also add, ... A type O person is not born with anti-A and anti-B. Just like any other foreign substance you have to get exposed to it in order to develop antibodies.