I am sure if you are totally sleep deprived for a long time you could possibly die or do something insane like hurt yourself but I have never heard of anyone dying from insomnia.
2006-10-20 13:35:36
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answer #1
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answered by Anonymous
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Fatal familial insomnia (FFI) is a very rare autosomal dominant inherited disease of the brain. The dominant gene responsible has been found in just 28 families worldwide; if only one parent has the gene, the offspring have a 50:50 chance of inheriting it and developing the disease. The disease's genesis and the patient's progression into complete sleeplessness is untreatable, and ultimately fatal.
It was first detected by Italian doctor Ignazio Roiter in 1979, who discovered two women from one family who apparently died of insomnia. Family records showed a history of seemingly related deaths. When another member of the family fell ill in 1984, his deterioration was studied and after his death, his brain was flown to the U.S. for further investigation.
In the late 1990s, researchers discovered that the disease is caused by a mutation in a protein called a prion protein (PrP): asparagine-178 is replaced by aspartic acid. The mutation changes the shape of the protein so that it becomes a prion and makes other, normal protein molecules change to the abnormal shape.
This causes plaques to develop in the thalamus, the region of the brain responsible for regulation of sleep. This first results in insomnia, and then progresses to more serious problems over time.
The age of onset is variable, ranging from 30 to 60, with an average of 50. Death usually occurs between 7 to 36 months from onset. The presentation of the disease varies considerably from person to person, even among patients from within the same family.
The disease has four stages, taking 7 to 18 months to run its course:
1. The patient suffers increasing insomnia, resulting in panic attacks and phobias. This stage lasts about four months.
2. Hallucinations and panic attacks become noticeable, continuing about five months.
3. Complete inability to sleep is followed by rapid loss of weight. This lasts about three months.
4. Dementia, turning unresponsive or mute over the course of six months. This is the final progression of the disease, and the patient will subsequently die.
There is no cure or treatment for FFI; hopes rest on the so far unsuccessful gene therapy. Sleeping pills have no effect.
There are other diseases involving the mammalian prion. Some are transmissible (TSEs) such as kuru, bovine spongiform encephalopathy (BSE, also known as "mad cow disease") in cows, and chronic wasting disease in American deer and American elk (in some areas of the Rocky Mountains). Some forms of congestive heart failure are also believed to be caused by variant prion, as well as Creutzfeldt-Jakob disease (CJD). These are generally not considered to be transmissible, except by direct contact with infected tissue, such as cannibalism, transfusion or transplantation.
But.....you sleep atleast a little....Take some Sleepinol...Drink some beer.....Your not going to die unless you have this disease.
2006-10-23 04:44:49
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answer #2
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answered by agentsmith015 1
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Well, it's like diabetes, nobody dies from it but dies because of the complications that it brings.
I work in an hospital and I've seen cases of untreated insomniacs who have developed mental problems, hallucinations, have become paranoid about someone or something chasing them to hurt or kill them and these people were not on any drugs that could've caused this.
Don't be worried, it'll only all the more keep you awake! Follow the advice of your doctor, it's not incurable nor terminal, you know.
2006-10-20 20:41:26
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answer #3
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answered by ivy 2
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sleep deprivation is not good - but I doubt your body will let you get so bad you will die! Many people live with it, night works are forced to cope with it, so it is unlikely
2006-10-20 22:34:38
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answer #4
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answered by rose_merrick 7
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insomnia cant get no sleep what a world you must life in... STOP WORRIING thats keeping you from sleep
2006-10-20 20:37:15
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answer #5
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answered by Anonymous
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I haven't heard of people dying. But worrying about it so much is not good.
2006-10-20 20:42:35
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answer #6
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answered by Avani 3
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actually, you can die from lack of sleep. One week with zero sleep and you die.
2006-10-20 22:22:37
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answer #7
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answered by Smo 4
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that just means you cant sleep restful but a mild sedative should take care of that. i don't believe you would die!!!!!!!!!!
2006-10-20 20:37:08
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answer #8
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answered by ash 4
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Apparently not. I've had it for five years and I'm still kicking.
2006-10-20 20:35:29
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answer #9
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answered by Mr. Peachy® 7
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I wouldn't think so, maybe you should ask your GP? Hope all goes well.
2006-10-20 20:42:07
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answer #10
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answered by Anonymous
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