Crohn’s disease is an ongoing disorder that causes inflammation of the digestive tract, also referred to as the gastrointestinal (GI) tract. Crohn’s disease can affect any area of the GI tract, from the mouth to the anus, but it most commonly affects the lower part of the small intestine, called the ileum. The swelling extends deep into the lining of the affected organ. The swelling can cause pain and can make the intestines empty frequently, resulting in diarrhea.
Crohn’s disease is an inflammatory bowel disease, the general name for diseases that cause swelling in the intestines. Because the symptoms of Crohn’s disease are similar to other intestinal disorders, such as irritable bowel syndrome and ulcerative colitis, it can be difficult to diagnose. Ulcerative colitis causes inflammation and ulcers in the top layer of the lining of the large intestine. In Crohn’s disease, all layers of the intestine may be involved, and normal healthy bowel can be found between sections of diseased bowel.
Crohn’s disease affects men and women equally and seems to run in some families. About 20 percent of people with Crohn’s disease have a blood relative with some form of inflammatory bowel disease, most often a brother or sister and sometimes a parent or child. Crohn’s disease can occur in people of all age groups, but it is more often diagnosed in people between the ages of 20 and 30. People of Jewish heritage have an increased risk of developing Crohn’s disease, and African Americans are at decreased risk for developing Crohn’s disease.
Crohn’s disease may also be called ileitis or enteritis.
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What causes Crohn's disease?
Several theories exist about what causes Crohn’s disease, but none have been proven. The human immune system is made from cells and different proteins that protect people from infection. The most popular theory is that the body’s immune system reacts abnormally in people with Crohn’s disease, mistaking bacteria, foods, and other substances for being foreign. The immune system’s response is to attack these “invaders.” During this process, white blood cells accumulate in the lining of the intestines, producing chronic inflammation, which leads to ulcerations and bowel injury.
Scientists do not know if the abnormality in the functioning of the immune system in people with Crohn’s disease is a cause, or a result, of the disease. Research shows that the inflammation seen in the GI tract of people with Crohn’s disease involves several factors: the genes the patient has inherited, the immune system itself, and the environment. Foreign substances, also referred to as antigens, are found in the environment. One possible cause for inflammation may be the body’s reaction to these antigens, or that the antigens themselves are the cause for the inflammation. Some scientists think that a protein produced by the immune system, called anti-tumor necrosis factor (TNF), may be a possible cause for the inflammation associated with Crohn’s disease.
2006-10-18 23:27:50
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answer #1
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answered by Anonymous
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Crohn's disease maybe?
Crohn's disease (also known as regional enteritis or CD) is a chronic, episodic disease which can affect any part of the gastrointestinal tract from mouth to anus. Because it is a systemic disease, it can also cause complications outside of the gastrointestinal tract.[1][2] The main gastrointestinal symptoms are abdominal pain and diarrhea, which may be bloody. Symptoms outside the gastrointestinal tract include skin rashes, arthritis, and ulcers in the mouth.
Crohn's disease is a type of inflammatory bowel disease (IBD). IBD occurs when the immune system contributes to damage of the gastrointestinal tract by causing inflammation. Crohn's disease can be difficult to distinguish from other forms of IBD such as ulcerative colitis. Because of the name, IBD can be confused with irritable bowel syndrome (IBS), a less serious condition.
Crohn's disease affects between 400,000 and 600,000 people in North America[3] Prevalence estimates for Northern Europe have ranged from 27–48/100,000.[4]
Although the cause of Crohn's disease is not known, it is widely believed to be an autoimmune disease. There is a genetic component to susceptibility, and the disease may be triggered in a susceptible person by environmental factors. Unlike the other major type of IBD, ulcerative colitis, there is no known medical or surgical cure for Crohn's disease.[5] Many medical treatments are however available for Crohn's disease with a goal of keeping the disease in remission.[6]
The disease was named after Burrill Bernard Crohn, an American gastroenterologist. In 1932, Crohn and two colleagues first described a series of patients with inflammation of the terminal ileum, the most common area affected in patients with Crohn's disease.
2006-10-18 23:31:51
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answer #2
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answered by Anonymous
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It is Crohn's disease . It is non specific granulamatous inflammation involving sharply demarcated single or multiple area of the intestine and probably a non specific pathological response to a variety of existing agents. Actually cause is unknown. Involvement of both genetic and environmental factors, - a)smokers are liable, b)Immunological factor mechanisms, c)infective agents, -Tuberculous Bacilli isolated from some patients, d)High intake of sugar and low intake of fibers usually. Usually 20-60 yrs are affected. but may occur in children , More in females.
2006-10-18 23:49:28
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answer #3
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answered by Anonymous
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Crohns Disease - look it up on the internet - there is a lot of stuff out there about it. The disease is quite painful and gives you the runs and upset tummys most days. There can be polyps and cancers and ulcers and all sorts of nasties in the bowel or stomach lining too. It is not a nice disease to have - makes one very tired and they are frequently in pain.
2006-10-18 23:27:35
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answer #4
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answered by Pooroldpossum 3
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this is one of those things that u might need to talk to a dietitian about. Crohn's disease affects each person differently such that different foods are triggers or irritants for each person, and a lot of sufferers cannot eat raw fruits and vegetables. i dont know what ur problem foods are, but i know a girl with Crohn's who was able to put on some weight by making shakes with protein powder, yogurt and/or ice cream, neutral-tasting oils like canola, and soft fruits like banana. good luck.
2016-05-22 01:35:02
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answer #5
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answered by Anonymous
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It's Crones Disease. Goggle it and u will get a wealth of info on it. Not a nice disease, give yr friend a lot of tlc.
2006-10-18 23:24:44
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answer #6
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answered by english_rose10 3
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I don't think there is any particular cause of it and there is no cure, my mom & nan have it.
Its not nice one min they are well the next they can be really pooly with it.
Your friend will need alot of support.
Good luck and I hope all goes well.
x x x x
2006-10-18 23:30:39
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answer #7
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answered by MoJoJoJo 4
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YES IT IS TO DO WITH THE BOWELS. well some find it hard to use their bowels while the other use them to many times. bad bad pains in the stomach my sister has also got this . a operation needs to be done. she was admitted with crucial pains in the stomach she could not use her bowels .
2006-10-18 23:27:31
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answer #8
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answered by ? 7
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Go to the following link for all the info you need, hope it is of help.
http://digestive.niddk.nih.gov/ddiseases/pubs/crohns/#what
2006-10-18 23:28:08
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answer #9
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answered by richard_beckham2001 7
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Crohns disease?I think it's a bit similar to IBS.It's not as bad as it sounds. Just lots of bowel problems and other stuff. Dunno what causes it though.
2006-10-18 23:36:07
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answer #10
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answered by crivvens.t21@btinternet.com 2
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