synthesis,release,metabolism,pathophysiology,physiological role in human body
2006-10-18 16:46:58 · 3 answers · asked by mahnoor l 1 in Science & Mathematics ➔ Medicine
GABA (gamma-amino butyric acid) is an inhibitory neurotransmitter, helping neurons stay selective about the signals to which they respond and helping produce a state of relaxation.
Neurons that produce GABA as their output are called GABAergic neurons, and have chiefly inhibitory action at receptors in the vertebrate.
Synthesis: Organisms synthesize GABA from glutamate using the enzyme L-glutamic acid decarboxylase and pyridoxal phosphate as a cofactor. It is worth noting that this involves converting the principal excitatory neurotransmitter (glutamate) into the principal inhibitory one (GABA).
Role: Drugs that act as agonists of GABA receptors (known as GABA analogues or GABAergic drugs) or increase the available amount of GABA typically have relaxing, anti-anxiety and anti-convulsive effects.♥
2006-10-18 21:55:14 · answer #1 · answered by ♥ lani s 7 · 0⤊ 0⤋
what isnt used is taken out of the synaptic cleft and surrounding elements by technique of astrocytes, truly the cleanup cells of the apprehensive gadget (they have a number of of different applications notwithstanding),
2016-12-04 23:52:46 · answer #2 · answered by lot 4 · 0⤊ 0⤋
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2006-10-18 23:27:39 · answer #3 · answered by Ivy 2 · 0⤊ 2⤋