In medical, what is PUVA Therapy? I would like to know about it.?

Answer 1

PUVA is a combination of psoralen (P) and long-wave ultraviolet radiation (UVA) that is used to treat many different skin conditions. Psoralens are compounds found in many plants which make the skin temporarily sensitive to UVA. The ancient Egyptians were the first to use psoralens for the treatment of skin diseases thousands of years ago.
Those patients requiring treatment to small areas only may be treated using the smaller hand and foot unit. 'Bathwater' PUVA may be suitable. In this case the hands and/or feet are soaked in a dilute solution of methoxsalen for 30 minutes, then immediately exposed to UVA.
I had this treatment for severe eczema on my hands. I tried all sorts of creams that didn't work and this was the only thing left. I was sceptical but it worked so well my hands have been so much better ever since. I can actually bend them now without them cracking and weeping.

Answer 2

PUVA Therapy is a kind of treatment combining Psoralen and Ultraviolet-A rays (UVA) or the so called phototherapy which is usually used for treatment of Eczema, Psoriasis and Vitiligo.

In this therapy, the Psoralen is applied or taken orally to sensitize the skin, then the skin is exposed to ultraviolet rays. The ultraviolet rays required is lessened with the use of Psoralen. Psoralens are photo sensitizing agents found in plants. They have been known since ancient Egypt but have only been available in a chemically synthesized form since the 1970s.

The mechanism of action probably involves activation of psoralen by UVA light which inhibits the abnormally rapid production of the cells . There are multiple mechanisms of action associated with PUVA, including effects on the skin immune system. Dark glasses must be worn during PUVA treatment because there is a risk of cataracts developing from exposure to sunlight. PUVA is associated with nausea, headache, fatigue, burning, and itching. Long-term treatment is associated with squamous-cell and melanoma skin cancers.♥

Answer 3

UV light treatment is a waste of time and money. Sorry, been there and done that. Natural sunlight works much better, loaded with vitamin D. I was using donovex at the time, started to see some clearing then it just stopped. Kept going for awhile without any results. I gave up on mondern medicanfor my psoriasis about 2 years ago. I "CURED" myself by going with alternative and natural healing after suffering for more than 20 years of doctor treatments. Good luck...you may have better results than I did with the light treatment.

Answer 4

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RE:
In medical, what is PUVA Therapy? I would like to know about it.?

Answer 5

Light Therapy

Light therapy (phototherapy) is given under the supervision of a physician. It is available in dermatologists’ offices, psoriasis day-care centers, phototherapy clinics, and some hospitals.
UVB:

Ultraviolet B (UVB) light waves have wavelength’s ranging between 290-320 nm. It is the wavelength in sunlight which is responsible for most of the sunburns; sometimes tar, anthralin, calcipotriol/calcipotriene, or tazarotene topical therapy is also used in conjunction with UVB phototherapy. In 1925, Goeckerman used tar in addition to UVB, the Ingram method refers to tar baths, topical anthralin, and UVB.

UVB is given to the whole body in a cabinet, or to localized areas with a small portable unit. Most UVB given is broadband UVB. Narrow band UVB, which has a wavelength of 311 nm, is available in certain centers. Some patients may do better with narrow band UVB, but the risk of a sunburn reaction may be greater.

The eyes need to be protected with special glasses during UVB treatment in order to prevent eye damage. Although treatment is often limited to 2-4 weeks, long term treatment might be associated with aging of the skin, burning, and potentially an increase in skin cancer. UVB is usually administered three times a week for three months for clearing and maintenance can be achieved by using it less frequently. Long remissions may occur after UVB phototherapy.