What is the difference between the Multiple Sclerosis and the Friedreich syndrom?

Question

My brother has something that goes between both of them and even doctors couldn't identify it.he also has a malformation of his feet bones.

Answer 1

Multiple sclerosis:

Abbreviated MS, also known as disseminated sclerosis.
Is a chronic, inflammatory disease that affects the central nervous system (CNS). MS can cause a variety of symptoms, including changes in sensation, visual problems, muscle weakness, depression, difficulties with coordination and speech, severe fatigue, and pain. Although many patients lead full and rewarding lives, MS can cause impaired mobility and disability in the more severe cases.

Multiple sclerosis affects neurons, the cells of the brain and spinal cord that carry information, create thought and perception and allow the brain to control the body. Surrounding and protecting some of these neurons is a fatty layer known as the myelin sheath, which helps neurons carry electrical signals. MS causes gradual destruction of myelin (demyelination) and transection of neuron axons in patches throughout the brain and spinal cord, causing various symptoms depending upon which signals are interrupted. The name multiple sclerosis refers to the multiple scars (or scleroses) on the myelin sheaths. It is thought that MS results from attacks by an individual's immune system on the nervous system and is therefore categorized as an autoimmune disease.

Multiple sclerosis may take several different forms, with new symptoms occurring in discrete attacks or slowly accruing over time. Between attacks, symptoms may resolve completely, but permanent neurologic problems often persist. Although much is known about how MS causes damage, its exact cause remains unknown. MS currently does not have a cure, though several treatments are available which may slow the appearance of new symptoms. MS primarily affects adults, with an age of onset typically between 20 and 40 years, and is more common in women than in men.

Friedreich Ataxia:

Friedreich's ataxia is an inherited disease that causes progressive damage to the nervous system resulting in symptoms ranging from gait disturbance and speech problems to heart disease. It is named after the German physician Nicholaus Friedreich, who first described the condition in the 1860s. "Ataxia," which refers to coordination problems such as clumsy or awkward movements and unsteadiness, occurs in many different diseases and conditions. The ataxia of Friedreich's ataxia results from the degeneration of nerve tissue in the spinal cord and of nerves that control muscle movement in the arms and legs. The spinal cord becomes thinner and nerve cells lose some of their myelin sheath the insular covering on all nerve cells that helps conduct nerve impulses.

Friedreich's ataxia, although rare, is the most prevalent inherited ataxia, affecting about 1 in every 50,000 people in the United States. Males and females are affected equally.

Friedreich's ataxia is an autosomal recessive congenital ataxia and is caused by a mutation in Gene X25 that codes for frataxin, located on chromosome 9. This protein is essential in neuronal and muscle cells for proper functioning mitochondria and the mutation causes inadequate production of frataxin. This results in, among other things, a degeneration of nerve tissue in the spinal cord.

Delatycki et al. (2000) provided an overview of the clinical features, pathology, molecular genetics, and possible therapeutic options in Friedreich ataxia.

Friedreich's ataxia and muscular dystrophy, though often compared, are completely different diseases. Muscular dystrophy is the result of muscle tissue degeneration whereas Friedreich's ataxia is the result of nervous tissue degeneration caused by a trinucleotide repeat expansion mutation. Both are researched by the Muscular Dystrophy Association.

There are two types, the classic form and one in association with a genetic vitamin E deficiency. They cannot be distinguished clinically.

Answer 2

Scoliosis is not an autoimmune disease - it is simply a curvature of the spine and creates a not perfectly straight spine especially when bending forwards and can (in extreme forms if progressing - (most stay the same ) be disabling) Generally speaking it is a benign condition and not of great cause for concern MS or multiple sclerosis is an autoimmune disease which attacks the central nervous system's conduction system (the insulation on the nerves) and causes often severe disability over years. There are different forms and some progress quickly causing disability over years others can come, get better, get worse but still progress over years. If your friend has been diagnosed (BY A DOCTOR) she should know if she has MS - it is a VERY serious diagnosis. I have a mild scoliosi in my spine and it causes me no bother whatsoever, If i had MS i would be pushing for maximal therapy input and medications to control it ASAP Please don't confuse these conditions any more - they are worlds apart and shouldnt be thought of in the same breath, Hope this helps - please see a doctor - they are free in this country.

Answer 3

Your brother is blessed to have you as his sister...

I hope this information helps.

Multiple Sclerosis and Friedreich's Ataxia have many of the same physical symptoms.

Some differences between Multiple Sclerosis and Frederich's Ataxia are as follows...

Multiple Sclerosis-

Multiple Sclerosis can be treated by relieving the symptoms. Doctors prescribe muscle relaxants to help ease muscle spasms. Some patients find that corticosteroid drugs shorten acute attacks of the disease by reducing inflammation of the nerve tissue.

Besides drugs, many patients are more comfortable if they are well rested. Afternoon naps and adequate sleep at night offer some relief. In addition, cold temperatures sometimes improve symptoms, whereas heat makes them worse.

Friedreich's Ataxia-

Friedreich's ataxia, the commonest form of ataxia, causes curvature of the spine (scoliosis) and damages heart tissue.

Answer 4

Multiple sclerosis is one of the most debilitating and discouraging conditions anyone can have. Waking up day after day knowing you are stricken with MS that gradually drags you, healthy young person, toward chronic illness and maybe shorter life. Suddenly you no longer expect to enjoy many of life's greatest experiences. The inside story on Dr. Gary remarkable Multiple Sclerosis cure

Read on to discover what really causes your multiple sclerosis!

Answer 5

1