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I'm an RN who has taught nursing for over 25 years and although I understood your question I had to look the answer up. The challenge is trying to simplify the answer in terms that you might understand but I will do my best. The real question is, What does Proteus vulgaris mean and how does the Weil-Felix reaction relate to it? First of all, Proteus infections consist of gram-negative bacilli (bacteria). One of the four strains of Proteus is called P. vulgaris or Proteus vulgaris. Some strains of P. vulgaris share a common antigen (a substance that induces the formation of antibodies which act specifically with it) with certain rickettsia. This accounts for the appearance of antibodies against Proteus organisms known as the Weil-Felix reaction in typhus, scrub typhus, and Rocky Mountain Spotted Fever. The Weil-Felix and complement fixation tests are useful for routine diagnosis of rickettsial diseases. The Weil-Felix test gives positive results in patients with spotted fever and murine typhus and negative results in those with rickettsialpox and Q fever. This explanation involves advanced Immunology so it is difficult to explain the concepts involved without covering a basic level of Immunology first. Hopefully this information will be helpful to you. Good luck.

2006-10-08 18:28:06 · answer #1 · answered by marnie 3 · 0 0

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