Has anyone heard of FAP (Familial Adenomatous Polyposis) and has the disease..?

Question

I have it, found out about 7 years ago, and had an ileo-rectal anastomosis, and need to go back in for another op or two and just wondering if there is anyone else who has this, or knows anyone, as the only people that I know that have this are my family. My hubby and I are planning another baby, but I has to much trouble with the first one (painwise) and wondering if hormones can speed up the growth of polyps? (hope this isn't to confusing... it's confusing me lol) Thanks = )

Answer 1

I know of FAP, it is a painful disorder because of risks but birth control, pregnancy hormones etc should not interfere with FAP, feel free to ask your doctor or your OB, good luck

Answer 2

Familial adenomatous polyposis (FAP) is the most common adenomatous polyposis syndrome. It is an autosomal dominant inherited disorder characterized by the early onset of hundreds to thousands of adenomatous polyps throughout the colon. If left untreated, all patients with this syndrome develop colon cancer by age 35-40 years. In addition, an increased risk exists for the development of other malignancies.

The genetic defect in FAP is a germline mutation in the adenomatous polyposis coli (APC) gene. Syndromes once thought to be distinct from FAP are now recognized to be, in reality, part of the phenotypic spectrum of FAP. Syndromes with a germline mutation in the APC gene include FAP, Gardner syndrome, some families with Turcot syndrome, and attenuated adenomatous polyposis coli (AAPC). Gardner syndrome is characterized by colonic polyposis typical of FAP, along with osteomas (bony growth most commonly on the skull and the mandible), dental abnormalities, and soft tissue tumors. Turcot syndrome is characterized by colonic polyposis typical of FAP, along with central nervous system tumors (medulloblastoma). AAPC is characterized by fewer colonic polyps (average number of polyps, 30-35) as compared to classic FAP. The polyps also tend to develop at a later age (average age, 36 y), and they tend to involve the proximal colonic area.

Answer 3

additionally stated as Gardner's syndrome. the respond relies upon on the place the gene mutation is on your fiance. while FAP effects from mutations contained in the APC gene, it truly is inherited in an autosomal dominant development, meaning one reproduction of the altered gene in each and each cellular is sufficient to reason the ailment. in maximum circumstances, an affected offspring has one be certain with the difficulty. while FAP effects from mutations contained in the MUTYH gene, it truly is inherited in an autosomal recessive development, meaning the two copies of the gene in each and each cellular have mutations. often, the mothers and dads of a teenager with an autosomal recessive difficulty each and each carry one reproduction of the mutated gene, yet do no longer teach signs and indications of the difficulty. i could possibility a wager that your fiance has a mutation contained in the APC gene (adenomatous polyposis coli gene) as he has the difficulty as a replace of being asymptomatic and in basic terms donning the MUTYH gene. My suggestion to you the two is to get carry of genetic counseling earlier you marry. in case you & your fiance have little ones, each and each baby has a a million in 2 risk (50% risk) of inheriting the mutated gene and bobbing up the two FAP or a variation. each and each baby additionally has a 50% risk of no longer inheriting the mutation. it truly is a 50/50 risk in the two course. no longer good odds in any respect.

Answer 4

I don't have it, but you can get info at:
http://ghr.nlm.nih.gov/condition%3Dfamilialadenomatouspolyposis