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If u can explain me point wise will b better.

2006-10-01 00:26:20 · 2 answers · asked by Dr. Joe 3 in Health Diseases & Conditions Infectious Diseases

2 answers

My very simple lay understanding of it is ?????????????

2006-10-01 00:37:24 · answer #1 · answered by Anonymous · 0 0

A disease that is endemic in many tropical countries

Causative agent: Plasmodium spp.

Signs and symptoms: Patients suffering from malaria have intermittent fever

The malaria parasite attacks liver cells and red blood cells, reproducing asexually. Thousands of them are released into the blood stream and the toxins produced by these parasites cause fever

Tertian malaria - fever occurs every 48 hours

Quartan malaria - fever occurs every 72 hours

Benign - disease that is seldom fatal

Malignant - disease that is severe or usually fatal
Malaria has been treated with quinine since 1638. This is an extract from the cinchona tree . Quinine suppresses the growth of the protozoans in the bloodstream. In 1930 a drug named atrobine came into use . This drug was more effective than quinine and did not have the same toxic side effects. In 1945 another new drug named chloroquine came on the market and was found to be extremely effective in preventing and virtually curing jungle fever. It also had less toxic effects than either of the other drugs. However, it has recently been found that the plasmodia which cause jungle fever, have been shown to be developing resistance to chloroquine and other synthetic malaria drugs. In strains resistant to chloroquine and synthetic drugs, quinine is still used.

Work is been carried out to develop a malaria vaccine and several are undergoing clinical trials in human volunteers to test safety and effectiveness.

2006-10-01 07:29:45 · answer #2 · answered by Linda 7 · 0 0

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