In 1957 who for the first time succeeded in transplanting or grafting of bone marrow?

Question

May be a french scientist. MAYBE

Answer 1

In 1957, ED Thomas gave bone marrow intraveneously. See the bone marrow overview at http://www.washington.edu/research/pathbreakers/1955a.html,

A Nature report on classic articles, http://www.nature.com/ni/focus/hemato_stemcells/classics/1950,.html calls this "A successful first attempt at bone marrow transplantation in humans for the treatment of a hematological malignancy."

Thomas published his work in:
Intravenous infusion of bone marrow in patients receiving radiation and chemotherapy.
Thomas E. D., Lochte H. L. Jr, Lu W. C. & Ferrebee J. W.
N. Engl. J. Med. 257, 491—496 (1957)

Answer 2

Bone marrow transplantation (BMT) or hematopoietic stem cell transplantation (HSCT) is a medical procedure in the field of hematology and oncology that involves transplantation of hematopoietic stem cells (HSC). It is most often performed for people with diseases of the blood or bone marrow, or certain types of cancer. Bone marrow transplantation was pioneered at the Fred Hutchinson Cancer Research Center in the 1960s and 1970s by E. Donnall Thomas, whose work was later recognized with a Nobel Prize in Physiology and Medicine. Dr. Thomas' work showed that bone marrow cells infused intravenously could repopulate the bone marrow and produce new blood cells. His work also reduced the likelihood of developing a life-threatening complication called Graft-versus-host disease (GVHD). However it remains a risky procedure and it is reserved for patients with life threatening diseases.

Answer 3

you're real in that cord blood would be utilized in bone marrow transplants. in spite of the undeniable fact that, it introduces lots of issues into the equation. First, it quite is very not likely that your infant could be a tournament on your grandmother. employing cord blood provides some leeway on the tournament, in spite of the undeniable fact that it remains not likely. or maybe nevertheless there is leeway, a mismatch nonetheless has a extra robust danger of rejection or the affected person arising gvhd. 2d, opportunities are high that your infant's one unit of cord blood should not be adequate to help transplant in an person. One unit of cord blood quite purely has adequate stem cells to help transplant in a small infant. So, to apply the cord blood, she might would desire to bypass to the conventional public cord blood economic corporation and locate yet another unit that became an exact tournament on your infant's cord blood. additionally, cord blood takes longer to engraft than marrow or peripheral blood stem cells. The longer the transplant takes to engraft, the longer the affected person has 0 immune gadget, and the longer the affected person is with none style of immune gadget, the better probabilities of an infection. the probability is probable low, yet its not impossible. you will desire to communicate over along with her medical doctors to be certain if she is a candidate for cord blood transplant - so a ways as i understand they're nonetheless in scientific trials for adults. If she is possibly a candidate for this scientific care, you will possibly desire to privately economic corporation the cord blood, and her scientific medical doctors will desire to take an huge scientific history from you and all that. DONT lie approximately something.