Can Stevens-Johnson Syndrome be a side effect of Ibuprophen?

Answer 1

IB is considered an NSAID and this syndrome can come from a reaction to NSAIDs but as you will see from the exerpt from a website below - it does not mention IB as one of the drugs that can cause this. However IB IS an NSAID which CAN cause this so I am sure it would be possible but not in this case.

Your friend is not suffering the other symptoms like severe anxiety, pain, etc.. and the others that come up when you search for this syndrome online. Your friend is having an allergic reaction to something and if this is scaly - is it psorasis. I guess it would be possible BUT your friend is not having these other symptoms so it is most likely - not this but only a doctor - a dermatologist would be able to rule this out 100%. Also - this syndrom is fatal and your friend is just exhibiting a rash behind his ears - not excessive pain, etc - read below for all of the symptoms - none of which mention a rash behind the ears - at all since the ears - behind the ears is NOT a mucous membrane.- which this syndrome does involve.

Steven Johnson syndrome involves mucous membranes - mouth, nose, throat, privates, etc - anywhere your body is wet essentially - this is NOT this syndrome - not at all. Although -it can involve skin lesions, the way you describe their syptoms indicate psoriasis not this - I doubt it - pretty certain this is NOT it - the other one is much more common and is often found in the location you mention and also under the hairline, under the hair, around it, etc.


Symptoms of Stevens-Johnson Syndrome
Typically, Stevens-Johnson syndrome affects the mucous membranes of the oral cavity, nostril, eyes, and both the anal and genital regions. It may or may not be associated with skin lesions elsewhere on the body. Oropharyngeal (mouth) lesions may be so intolerable as to prevent eating, and there may be recurring oral ulcers. Often, the skin lesions may look like a target-lesion (3 concentric zones of color change) or as bullae (bubble-like).

A painful conjunctivitis may occur in the eye, frequently with a pus discharge, and can lead to corneal scarring and loss of vision. In addition to the mucous membrane lesions, fever and exhaustion are usual.

Approximately one-third of patients have pulmonary involvement with cough and patchy infiltrates (material that has permeated into the tissues) on chest x-ray. In fatal cases, renal failure and pneumonia may occur.

Stevens-Johnson Syndrome is a potentially deadly skin disease that usually results from a drug reaction. Another form of the disease is called Toxic Epidermal Necrolysis, and again this usually results from a drug-related reaction. Drugs that have been linked to Stevens-Johnson Syndrome include NSAIDS (non-steroid anti-inflammatory drugs), Allopurinol, Phenytoin, Carbamazepine, barbiturates, anticonvulsants, and sulfa antibiotics. In some cases, the condition is caused by a bacterial infection, and in many cases there is no known cause for the onset of Stevens-Johnson Syndrome or Toxic Epidermal Necrolysis.

These skin diseases can cause massive pain, suffering and anxiety. People that have taken or are taking medications such as the ones mentioned above are urged to familiarise themselves with the symptoms of SJS (Stevens-Johnson Syndrome) and Toxic Epidermal Necrolysis (TEN). This will enable you to seek immediate medical attention should the need arise, and early initiation of treatment can make a big difference to the seriousness of the disease as this can stop any secondary infections.

The aim of this site is to keep people informed about the symptoms, causes and treatment of SJS and TEN, and also to offer advice with regards to the legal options of those affected by these diseases. You can find out more about various aspects of these diseases through the following articles:

http://www.skinassn.org/

Answer 2

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Answer 3

Ibuprophen is not the medicine to treat Stevens Johnson synadrome. First understand what is Stevens-Johnson Syndrome -
Stevens-Johnson syndrome (SJS) is a severe and life-threatening condition. It is thought to be a hypersensitivity complex affecting the skin and the mucous membranes. SJS has been classified as a severe expression of erythema multiforme (EM), and is sometimes referred to as erythema multiforme major. This terminology is not consistent; medical texts often distinguish between causes of SJS, referring to drug induced syndrome as SJS and applying the term erythema multiforme to viral etiology.

The correct treatment for this is -

Discontinue all medications, particularly those known to cause SJS reactions. Treatment is initially similar to that of patients with thermal burns, and continued care can only be supportive (e.g. IV fluids) and symptomatic (e.g. analgesic mouth rinse for mouth ulcer); there is no specific drug treatment (2002). Treatment with corticosteroids is controversial since it might aggravate the condition or increase risk of secondary infections. Other agents have been used, including cyclophosphamide and ciclosporin, but none have exhibited much therapeutic success. Other common supportive measures include the use of topical pain anesthetics and antiseptics, maintaining a warm environment, and intravenous analgesics.

Please also consult a good physician and take treatment properly and you will be alright

Answer 4

In low single doses (200 to 400 mg) and daily doses of up to 1,200 mg the incidence of side effects is low. However, in patients treated on a long-term basis with more than 1,200 mg daily discontinuation rates are as high as 10 to 15%.

Common adverse effects include: nausea, dyspepsia, gastrointestinal ulceration/bleeding, raised liver enzymes, diarrhoea, headache, dizziness, salt and fluid retention, hypertension.[5]

Infrequent adverse effects include: oesophageal ulceration, heart failure, hyperkalaemia, renal impairment, confusion, bronchospasm, rash.

Stevens-Johnson Syndrome Causes:
The cause of SJS is either infections (usually following viral infections such as herpes simplex virus, influenza, mumps, cat-scratch fever, histoplasmosis, Epstein-Barr virus, or similar), induced by allergic reactions to drugs, (valdecoxib, penicillins, barbiturate, sulfas, phenytoin, lamotrigine, nevirapine[1][2]), malignancy-related (carcinomas and lymphomas), or idiopathic (up to 50% of the time). SJS has also been consistently reported as an uncommon side effect of herbal supplements containing ginseng.

Answer 5

isnt it cat stevens????????