extreme sensitivity to pain. Sometimes someone will say they have a low pain tolerance and this is what they mean. Anytime you see the prefix hyper it will mean high or much. Algesia means pain. You have heard aspirin referred to as an analgesia? It simply means an anti-pain treatment.
2006-09-26 11:25:53
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answer #1
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answered by jidwg 6
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This is what I found on webmd.com
Hyperalgesia is a condition of altered perception such that stimuli which would normally induce a trivial discomfort cause significant pain.
Hyperalgesia is often a component of a neuropathic pain syndrome.
2006-09-26 11:32:10
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answer #3
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answered by Boricua Born 5
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Hyperalgesia is an extreme sensitivity to pain, which in one form is caused by damage to nociceptors in the body's soft tissues.
Hyperalgesia can be experienced in focal, discrete areas, or as a more diffuse, body-wide form. Conditioning studies have established that it is possible to experience a learned hyperalgesia of the latter, diffuse form. The focal form is typically associated with injury, and is divided into two subtypes:
Primary hyperalgesia describes pain sensitivity that occurs directly in the damaged tissues.
Secondary hyperalgesia describes pain sensitivity that occurs in surrounding undamaged tissues.
Hyperalgesia is induced by Platelet Aggregating Factor (PAF) which comes about in an inflammatory or an allergic response. This seems to occur via immune cells interacting with the peripheral nervous system and releasing pain-producing chemicals (cytokines and chemokines) (see Marchand, Perretti, & McMahon, 2005).
One unusual cause of focal hyperalgesia is platypus venom.
Ikeda, Stark, Fischer, Wagner, Drdla, Jäger, et al. (2006) showed that stimulation of pain fibres in a pattern consistent with that from inflammation switched on a form of amplification in the spinal cord, long term potentiation. This occurred where the pain fibres contacted a pain pathway, the periaqueductal grey. Ikeda et al. argued that amplification in the spinal cord is another way of producing hyperalgesia
2006-09-26 11:23:24
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answer #4
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answered by msmidnight30 2
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Hyperalgesia is a condition of altered perception such that stimuli which would normally induce a trivial discomfort cause significant pain.
Hyperalgesia is often a component of a neuropathic pain syndrome.
2006-09-26 11:22:41
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answer #5
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answered by eric_themadman 2
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