What diseases arise out of faulty mechanisms dealing with RNA trancription or translation?

Answer 1

many diseases have been linked to a faulty RNA transcription or translation.Few examples are as follows:
*Phenylketonuria (PKU)
*Cystic fibrosis
*Sickle cell anemia
*cancer
* AIDS

Answer 2

Of course, transcription and translation control the production of every gene product so global problems with either of these processes would be lethal. However, recent data indicate that there are certain identified mutations that lead to changes in the efficiency of either of these processes for a specific gene and its product. As an example, there have been mutations associated with certain cases of Fragile X syndrome where the mutation is not in the coding sequence of the transcript but is in the untranslated region and this leads to reduced efficiency for mRNA translation.

Answer 3

Very common here is Down's syndrome..the cell doesn't get the correct number of chromosomes and of course...its bad. I think there is another one called Klinefelters or Klinefellers syndrome and the one common in Jewish people..I can't remember what its called..but its common in a specificy type of jewish descendant.