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I don't see how it is pharmacologically possible for narcotic (or opioid) analgesics to act synergistically with caffeine. Opioids act on opioid receptors in the central nervous system, while caffeine does not affect those receptors in any way.

2006-09-20 14:34:00 · answer #1 · answered by Kokopellimana 2 · 0 0

Supposedly it works with any pain killer. According to an osteopath I saw.

2006-09-20 13:46:35 · answer #2 · answered by Patti C 7 · 0 0

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