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This is for research for my psychological thriller, when my main character was diagnosed with Aplastic Anemia, and needed a bone marrow transplant. But is it possible that someone else other than your family is a match, when they don't match? And if so, what are the odds and percentage of that? Anyone who had Aplastic Anemic or in the health field would be great to answer this.

2006-09-19 07:30:02 · 7 answers · asked by Kristen H 6 in Health Diseases & Conditions Other - Diseases

7 answers

Yes it is common for family members to not be a match. Though the odds are higher for siblings to be a match than the general population. Just last week we had an O Pos mom have twins: one girl was A Neg and twin sister was B Pos. Dad must be AB Pos or AB Neg (or there were 2 dads!!!). Mom can donate blood to the B Pos child, but otherwise, the children are blood type incompatible to each other and to mom.
In addition to ABO groups tho, the HLA matching is more important, and sometimes as a result of a bone marrow transplant the recipient ends up a different blood type than the original! So for example, your B Neg Aplastic Anemia patient that has a bone marrow transplant could end up A Pos.
You could have a scenario where the blood sample DNA at a crime scene does not match the suspect because of the secret (or overlooked) treatment of the suspect - providing that the sample was left prior to the treatment . or whatever...... :)

2006-09-19 08:43:02 · answer #1 · answered by petlover 5 · 0 0

It's entirely possible for a family member not to match, because of how complex genetics are. Very often family members are not good matches when a stranger can be a perfect match. I am by no means an expert - you might find some good info by "googling", doing a search & going to some trandplant sites.

2006-09-19 07:35:11 · answer #2 · answered by Julep 3 · 0 0

Yes it is possible to get a match from someone not related to you. It happens all the time but it's difficult to find because more people need to be tested and rgistered as potential bone marrow donors. Thanks for your ?. It allows me to promote the need for organ/bone marrow donors everywhere.

2006-09-24 11:00:31 · answer #3 · answered by PROUDJEW 4 · 0 0

It is very possible that you wont find a familiar match but find one outside the family. Percentages for that are hard because of the variances but it happens frequently.

2006-09-19 07:54:46 · answer #4 · answered by NotSoTweetOne 4 · 0 0

Yes except for identical twins the possibility of not matching is high.

2006-09-19 07:32:42 · answer #5 · answered by Anonymous · 0 0

Yes it`s possible,If we have blood group un-matching

2006-09-19 07:34:12 · answer #6 · answered by Easternwind 2 · 0 0

yes its possible

2006-09-24 14:21:47 · answer #7 · answered by duc602 7 · 0 0

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