Can paracetamol have an adverse reaction if taken with Lamictal?

Question

I caught a throat infection with a headache and temperature a few weeks ago, so I took a paracetamol to get the temperature down. A few days later, my memory (long and short term) had gone completely. The same happened to me about a year ago for the first time and I was wondering whether the paracetamol had reacted with the Lamictal I take for epilepsy. I will make more informed inquiries (with the doctor etc.) but would be interested to hear if others have had similar experiences. Many thanks.

Answer 1

paracetamol aka tylenol can interact with lamictal by the way that they are both metabolised in the liver. One dose will most likely have no interaction, also the toxicity of paracetamol does not include memory problems and toxicity of lamictal is not likely with one dose of paracetamol, good luck, i am hearing this name after 3-4 years

Answer 2

Lamotrigine side effects

Get emergency medical help if you have signs of an allergic reaction: hives; fever; swollen glands; painful sores in or around your eyes or mouth; difficulty breathing; swelling of your face, lips, tongue, or throat.
Seek emergency medical attention if you have signs of a life-threatening skin rash: fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
If you have to stop taking lamotrigine because of a serious skin rash, you may not be able to take it again in the future.
Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, depression, anxiety, or if you feel agitated, hostile, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.
Call your doctor at once if you have:
- the first sign of any skin rash, no matter how mild;
- changes in your menstrual periods;
- low blood cell counts--flu-like symptoms, swollen gums, mouth sores, skin sores, rapid heart rate, pale skin, easy bruising, unusual bleeding, feeling light-headed;
- possible signs of brain inflammation--fever, chills, headache, neck stiffness, increased sensitivity to light, purple spots on the skin, confusion, drowsiness; or
- signs of inflammation in your body--swollen glands, severe tingling or numbness, muscle weakness, upper stomach pain, jaundice (yellowing of the skin or eyes), chest pain, new or worsening cough with fever, trouble breathing.
Common side effects may include:
- headache, dizziness;
- blurred vision, double vision;
- tremor, loss of coordination;
- dry mouth, nausea, vomiting, stomach pain, diarrhea;
- fever, sore throat, runny nose;
- drowsiness, tired feeling;
- back pain; or
- sleep problems (insomnia).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)


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