The condition is called Myasthenia Gravis a kind of neurological condition. To quote from the the US national institute of neurological disorders and stroke " Myasthenia gravis is a chronic autoimmune neuromuscular disease characterized by varying degrees of weakness of the skeletal (voluntary) muscles of the body. The name myasthenia gravis, which is Latin and Greek in origin, literally means "grave muscle weakness." With current therapies, however, most cases of myasthenia gravis are not as "grave" as the name implies. In fact, for the majority of individuals with myasthenia gravis, life expectancy is not lessened by the disorder.
" Medications used to treat the disorder include anticholinesterase agents such as neostigmine and pyridostigmine, which help improve neuromuscular transmission and increase muscle strength. Immunosuppressive drugs such as prednisone, cyclosporine, and azathioprine may also be used."
2006-09-16 19:16:14
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answer #1
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answered by cehelp 5
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Do you mean "Myasthenia Gravis"?
Symptoms.
Vision changes:
Double vision
Difficulty maintaining steady gaze
Eyelid drooping
Patients with generalized disease may also have:
Swallowing difficulty, frequent gagging or choking
Weakness or paralysis (may worsen with exertion later in the day)
Muscles that function best after rest
Drooping head
Difficulty climbing stairs
Difficulty lifting objects
Need to use hands to rise from sitting positions
Difficulty talking
Difficulty chewing
Additional symptoms that may be associated with this disease:
Hoarseness or changing voice
Fatigue
Facial paralysis
Drooling
Breathing difficulty
Myasthenia gravis can usually be controlled with medication. Medication is used for two different endpoints:
Direct improvement of the weakness
Reduction of the autoimmune process
Treatment:-
Muscle function is improved by cholinesterase inhibitors, such as neostigmine and pyridostigmine. These slow the natural enzyme cholinesterase that degrades acetylcholine in the motor end plate; the neurotransmitter is therefore around longer to stimulate its receptor.
Immunosuppressive drugs such as prednisone, ciclosporin and azathioprine may be used. If the myasthenia is serious (myasthenic crisis), plasmapheresis is used to remove the putative antibody from the circulation. Similarly, intravenous immunoglobulins (IVIg) is used to bind the circulating antibodies.
Thymectomy, the surgical removal of the thymus gland (which is abnormal in myasthenia gravis patients), improves symptoms in more than 50 percent of patients, even in those without thymoma. Some patients are cured by thymectomy, suggesting that the thymus plays a significant role in the pathogenesis of myasthenia, but there has not been any direct connection and it cannot be considered a cure.
Please see the webpages for more details on Myasthenia Gravis.
2006-09-17 02:20:02
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answer #2
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answered by gangadharan nair 7
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