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My dad apparently was taking his medicine wrong, and his Coumadin level was way to high in April. All that has been resolved, but now his body is not metaolizing his medications correctly.

He is in the hospital now because his Dijoxin level got way to high and he nearly died.

Any suggestions on what would cause your body not to metobalize medications correctly would be great.

2006-09-16 16:26:35 · 12 answers · asked by msloptician 2 in Health Other - Health

I guess I forgot to mention he does not have health insurance right now. He is disabled after double valve replacement and we are waiting until he is eligible for medicare in January. Until then he is on indigent care.

The doctors seem to be in hurry to treat him and are not looking deeply into what is going on. I guess I cannot blame them, because of no insurance. I am trying to do a little research myself so I will know what I should ask them to test for.

They will not test for anything unless we ask because the know he has no insurance. It also keeps us from being able to take him to a specialist, because we live in a small town and can only be treated in the county that is providing his indigent care.

2006-09-16 17:35:11 · update #1

12 answers

Coumadin is perscribed to thin the blood for people who have had blood clots or are at risk for them. Its unlikely that too much Coumadin caused kidney damage. When the dose is too high it, it can cause bleeding which can be minor or serious like a stroke or gastrointestinal bleeding. The Coumadin dose has to be individualized for each person and is typically determined by performing a test called the INR test every so often. The dose of Coumadin is adjusted to keep the INR within a range that should keep the blood thin enough to reduce the risk of a blood clot but not so thin that the person should have a lot of bleeding. However, many things may interact with Coumadin and result in the INR being too high or low for the particular dose including different medications, foods and other medical problems.

Digoxin is primarily excreted from the body by the kidney so kidney damage can result in an increased level of digoxin in the body. So can a number of other drugs or other medical problems. The digoxin level in the body can also be checked by a blood test and the dose adjusted so that the level is maintained in an effective but generally safe level.

Sounds like your dad needs to be followed closely by his doctors to make sure that the doses of medicine he takes are adjusted to account for any new medications he may take, changes in his diet or any changes to his kidney function (or liver function since the liver also metabolizes many medications). A good website that provides comprehensive information on medications is at http://www.rxlist.com/.

2006-09-16 17:11:58 · answer #1 · answered by Anonymous · 0 0

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2016-04-17 12:46:51 · answer #2 · answered by Wendy 3 · 0 0

2

2016-09-24 01:18:36 · answer #3 · answered by Danna 3 · 0 0

Coumadin Toxicity

2016-10-03 08:46:01 · answer #4 · answered by cluff 4 · 0 0

Coumadin is unlikely to cause kidney damage. It does thin the blood out so that bruising and bleeding can occur. If there is additional trauma to the kidney, then nasty bleeding can occur in the kidney (often seen as blood in the urine).

Digoxin is predominantly cleared renally.

Perhaps he has another cause of kidney problems - dehydration being the commonest.

Many other things can cause kidney troubles. Infections, prostate hypertrophy, kidney stones, drugs of various sorts, diabetes, autoimmune disease ...

Perhaps you should ask his doctors what has been going on?

The other things that cause poor metabolism of medications is liver disease (wiki says 16% hepatic metabolism ie 84% excreted unchanged), but digoxin is primarily cleared by the kidney.

2006-09-16 16:28:10 · answer #5 · answered by Orinoco 7 · 0 0

too a lot protein may reason kidney harm yet when is oftentimes uncommon. have you ever lengthy previous to the physician? perhaps you're peeing alot because you drank a lot water with all of your shakes? If this keeps occurring for the subsequent 2 days, truthfully bypass to the physician. I easily were eating protein shakes for over 6 years now. there are circumstances there I drink 3 shakes an afternoon (2 scoops in accordance to shake it really is 6 servings) and under no circumstances something occurs to me. My chum does an same so don't be anxious. be positive you spot physician if complications save persisting.

2016-11-27 19:39:24 · answer #6 · answered by ? 4 · 0 0

As mentioned in other responses, Coumadin overdose can cause bleeding which can occur in any organ. As far as metabolizing medications, it's the job of the liver. It sounds like your father's liver might be having trouble doing its job.

2006-09-16 16:32:29 · answer #7 · answered by sveta_dr_mom 3 · 0 0

Many overdoses affect the liver and kidneys, because they are the organs that filter the blood and urine. Therefore, overloading those organs with anything (alcohol, medicine, drugs) can do permanent damage to them. The best thing he can do is stay in contact with his doctor to make him aware of the problems.

2006-09-16 16:29:31 · answer #8 · answered by lucyfire24 2 · 0 0

Reverse Kidney Disease Naturally :
http://www.NaturallyGo.com/Help

2015-04-08 16:54:33 · answer #9 · answered by Jefferson 2 · 0 0

This is an interesting question, and one that has intrigued me for quite some time.

2016-08-23 06:58:26 · answer #10 · answered by Anonymous · 0 0

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