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I know one is regular Sudafed and the other is Sudafed PE and I know pseudo can be made into meth and so far phenyl can't, but why? They are both ephedrine based. No I'm not a cook, just curiousity.

2006-09-16 06:38:07 · 5 answers · asked by Anonymous in Science & Mathematics Medicine

Good answers, but I was looking more for the differences in chemical bonds.

2006-09-16 10:52:41 · update #1

5 answers

Pseudoephedrine is a sympathomimetic amine commonly used as a decongestant and only relieves nasal congestion. Phenylephrine is used as a decongestant too.

Pseudoephedrine a methamphetamine precursor .Oral phenylephrine is extensively metabolised by monoamine oxidase therefore, compared to orally-taken pseudoephedrine, it has a reduced and variable bioavailability of only up to 38 percent .

Pseudoephedrine can be used in various straightforward reactions for the clandestine manufacture of methamphetamine, while production of methamphetamine from phenylephrine is comparatively much more difficult.

Phenylephrine does not cause the release of endogeneous noradrenaline like pseudoephedrine does. Therefore, phenylephrine is less likely to cause side-effects like central nervous system stimulation, insomnia, anxiety, irritability and restlessness.

Phenylephrine has 3-(1-hydroxy-2-methylamino-ethyl) phenol
Pseudoephedrine has (1S,2S)-2-methylamino-1phenylpropan-1-ol

2006-09-16 11:46:16 · answer #1 · answered by ♥ lani s 7 · 4 0

I think phenylephedrine contains a compound to fight congestion that is different from psuedoephedrine in that it does not cause heart palpitations. There was a scandal over Dimetapp and other cold medicines used by children when it was found that the psuedoephedrine could increase heart rate (which is why they use it in speed). Cold medicines had to get smart or shut down, so phenylephedrine was used instead, because it does not cause heart problems. It really has no value to be used in meth, because it cannot (so far) produce the high that pseudoephedrine can. But I'm not totally sure about that.

2006-09-16 06:42:14 · answer #2 · answered by Anonymous · 2 0

Pseudoephedrine Hydrochloride Wiki

2016-12-16 13:37:10 · answer #3 · answered by ? 4 · 0 0

Phenylephrine or neosynephrine is an α-adrenergic receptor agonist used primarily as a decongestant, as an agent to dilate the pupil, and rarely to increase blood pressure.

Pseudoephedrine (commonly abbreviated as PSE) is a sympathomimetic amine commonly used as a decongestant. The salts pseudoephedrine hydrochloride and pseudoephedrine sulfate are found in many over-the-counter preparations either as single-ingredient preparations, or more commonly in combination with antihistamines, paracetamol and/or ibuprofen. It is often referred to by consumers as Sudafed, which is the trademark for a common brand of pseudoephedrine hydrochloride.

Unlike antihistamines, which modify the systemic histamine-mediated allergic response, pseudoephedrine only relieves nasal congestion commonly associated with colds or allergies. The advantage of oral pseudoephedrine over topical nasal preparations, such as oxymetazoline, is that it does not cause rebound congestion (rhinitis medicamentosa); however, it is more likely to cause adverse effects including hypertension

2006-09-16 06:43:48 · answer #4 · answered by sting 2 · 3 0

Pseudoephedrine is as the name suggests a copy of what is produced within the body as a stimulant and is like speed the drug and is not really good for you at all. Antihistamine is a drug that has been produced to control the effects of hayfever and has positive effects.

2016-03-17 21:56:01 · answer #5 · answered by Anonymous · 0 0

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