Enzymes consist mainly of protein,so do protein-hydrolytic enzymes,like pepsin,hydrolyse enzymes ?

Question

I take biochemistry course and I would like to know that enzymes hydrolysing proteins hydrolyse other one(enzymes) (or maybe themselves) or not?

Answer 1

Pepsin is an example. It is secreted as pepsinogen. The hydrochloric acid of the stomach converts a little into pepsin. This then cleaves more pepsinogen into pepsin eg see;

http://chemistry.umeche.maine.edu/CHY431/Peptidase14.html

"Pepsin is synthesized as a zymogen, which (as noted) is stable at normal physiological pH. When secreted into the stomach, at pH 3.5 or lower, it immediately undergoes autocatalytic cleavage of the 44-residue prosegment, producing active pepsin."

Answer 2

Yes enzymes like pepsin hydrolyse other enzymes and even hormones . Enzymes are biocatalists. Some enzymes like pepsin react only in acid medium of stomach and others in alkaline medium of jejunum..

Answer 3

All of the Above.. Enzymes are proteins that catalyze (i.e., increase the rates of) chemical reactions. In enzymatic reactions, the molecules at the beginning of the process are called substrates, and the enzyme converts them into different molecules, called the products. Almost all processes in a biological cell need enzymes to occur at significant rates. Since enzymes are selective for their substrates and speed up only a few reactions from among many possibilities, the set of enzymes made in a cell determines which metabolic pathways occur in that cell.

Answer 4

yes!protein-hydrolytic enzymes like pepsin can hydrolyse other enzymes &themselves . hence they are secreted as proenzymes(like pepsinogen) to avoid excoriation of tissues that arent lined by mucous membranes.moreover,they hav autocatalytic activity i.e,they convert pepsinogen to pepsin and since they are secreted only when enough substrate(protein) is present ,they hydrolyse the substrate rather than self destruction(pepsin hydrolysing pepsin itself)!!!

Answer 5

Enzymes are highly specific.If the enzyme recognises the other enzyme as the substrate it will catalyse the reaction.For that to happen there should be gross difference in the molecular architecture between the 2 enzymes !!

Answer 6

yes, i have studied that pepsine, trypsine n hysrolyse r all types of enzymes.
the enzyme amylase converts starch into maltose and the enzyme maltaze converts maltose into glucose.
the enzymes pepsine and trypsine converts protein into amino acids.
the enzyme lipase converts fat into fatty acids.!
GOOD LUCK FOR BOICHEMISTRY!!!!

Answer 7

YES THEY DO. HYDROLTYIC ENZYMES LIKE PEPSIN HYDROLIZE PROTEINS (THAT ALSO INCLUDES OTHER ENZYMES) BY CUTTING AT SPECIFIC AMINO ACID SEQUENCES. PEPSIN WILL NOT HYDROLYZE PROTIENS +ENZYMES IF pH IS ABOVE 2. AT THAT pH PEPSIN DOSEN'T WORK ANY MORE. THERE ARE OTHER ENZYMES THAT HYDROLIZE PROTIENS +OTHER ENZYMES NON-SPECIFICALLY .. THEY JUST RECOGNIZE PEPTIDE BOND AND CUT IT SINCE PROTEINS ARE MADE OF CHAIN OF AMINO ACIDS JOINED BY PEPTIDE BONDS