As in any form of hepatitis, patients in the acute stage should rest in bed as needed, eat a balanced diet, and avoid alcohol. Alpha-interferon, the natural body substance which helps control hepatitis C, has generally not been found helpful in treating hepatitis D. If the liver is largely destroyed and has stopped functioning, liver transplantation is an option. Even when the procedure is successful, disease often recurs and cirrhosis may actually develop more rapidly than before.
2006-09-13 01:24:45
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answer #1
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answered by Anonymous
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Hepatitis D is a disease caused by a small circular RNA virus (Hepatitis delta virus or hepatitis D virus, HDV); this virus is a subviral satellite. In a natural infection, it can only propagate in the presence of of another virus, the hepatitis B virus (HBV). When this transmission occurs simultaneously, it is called coinfection. When the hepatitis D virus infects cells previously infected with hepatitis B, it is called superinfection (diapatient don't have IgM anti-HBc).
Patients with coinfections have both IgM (antibody specific of acute primary infections) anti-HD and IgM anti-HBc, whereas superinfections are characterized by IgM anti-HD but not IgM anti-HBc.
Either superinfection or coinfection can seriously worsen the damage to the liver caused by hepatitis B, causing cirrhosis or hepatocellular carcinoma (liver cancer).
The tropical fever called Lábrea fever, detected in the Amazon for the first time, has been identified as a type of hepatitis D.
The hepatitis D virus genome consists of a negative sense single strand of RNA which forms a circular structure such that around 70% is Watson Crick base paired. With only 1700 nucleotides this virus has the smallest genome of any known to infect animals. It appears to have originated from a viroid which at some point acquired a cellular gene; the delta antigen.
Replication, using an RNA dependent RNA polymerase, first requires the formation of a positive sense RNA template from which a negative sense genome can be produced and part of this positive sense strand is cleaved to produce mRNA encoding the delta antigen.
There are two different forms of this antigen, which differ by 19 amino acids at the c-terminal, and the larger of the two associates with the RNA genome of the hepatitis B virus preventing its replication. It also directs packaging of HDV genomes into HBV particles.
2006-09-15 13:56:26
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answer #2
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answered by Anonymous
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Hepatitis D
Hepatitis D is a virus like substance that has been called the delta agent. It is the closest thing to a viroid that infects a human being. Some scientist class it as a viroid. It cannot proliferate without the presence of hepatitis B virus, because its genome lacks certain essential genes.
TREATMENT & MEDICAL MANAGEMENT
Acute HDV infection
Supportive care
Chronic HDV infection
interferon-alfa
liver transplant
2006-09-13 08:47:47
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answer #3
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answered by gangadharan nair 7
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Chelidonium majus is supposed to be a Homeo remedy for all hepatites.
2006-09-13 10:13:22
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answer #4
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answered by J.SWAMY I ఇ జ స్వామి 7
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