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If one were to get a large amount of blood transfused, due to an accident or something, would there be enough to change the majority of DNA in your blood? Enough even that police could incorrectly identify someone based on blood left behind at a scene of a crime?

2006-09-12 16:42:09 · 26 answers · asked by nslsuperstar 1 in Science & Mathematics Medicine

For those of you who think I'm trying to kill someone.... a "crime" left with blood DNA evidence could be any number of things (sickos). I could even be referring to having been the victim and they find the blood and want to make sure it matches me. The question is, if i had a major blood transfusion, would the blood that was found still match my DNA?

2006-09-12 17:02:58 · update #1

26 answers

Since the WBC's are the only nucleated blood cells, a complete blood transfusion would leave you with a blood DNA profile different from your own. If you were to undergo treatment for leukemia with a bone marrow transplant, this is what would happen after your bone marrow was wiped out with radiation. The DNA circulating would likely be from several donors. Your somatic DNA would not change. You would be severely immuno-compromised and not feeling up to any criminal shenanigans, so the threat to the crime fighters is negligable.

2006-09-13 12:54:33 · answer #1 · answered by davidosterberg1 6 · 0 0

If you had almost all your blood replaced, and then had it extracted and tested by the police very soon afterwards, it's possible that you could fool a DNA test. However, it is very difficult to change ALL a person's blood, and also the change would only last for a short time (say, a few weeks max) because the new blood cells your body creates to replace dead ones would carry your normal DNA.

Besides, the police could always just test something else instead, like skin cells. So the chances of fooling them at all aren't very good.

2006-09-12 23:46:39 · answer #2 · answered by Anonymous · 0 0

No. Your DNA is unique. The police normally take a swab from the inside of your mouth because the inside of your cheek is difficult to contaminate with other people's DNA (it is being washed all the time with your saliva and it produces a lot of new stuff).

Also, the amount of blood in your system to begin with is a lot higher than the amount of blood you might receive in a transfusion. A transfused sample would be the minority of the DNA and would be identified as a contaminant by the PD lab.

2006-09-12 23:46:35 · answer #3 · answered by Bernard B 3 · 1 0

A blood transfusion in the "past" does not alter your DNA.

I would hope that you are not thinking of doing something and think that you can get away with it. Vague memory of biochemistry. This answer would be much better answered by a Biochemist.

2006-09-13 00:07:04 · answer #4 · answered by dearestdawnte 3 · 0 0

No. There is no way to change your blood DNA. If you had a different kind of blood transfused into you, you would surely die!

2006-09-13 00:02:00 · answer #5 · answered by Chase H 2 · 0 0

nope.... wondering why you would want to....."Enough even that police could incorrectly identify someone based on blood left behind at a scene of a crime?"

2006-09-12 23:44:29 · answer #6 · answered by Anonymous · 0 0

You must mean 'blood type'. You can change the mixture, e.g. if you have blood type AB you can receive blood types A, B, AB, or O. But type O, can only receive from type O, so if you gave it type A, then all the major organs would reject it because they must have blood type O. So the answer is NO.

2006-09-12 23:52:31 · answer #7 · answered by Anonymous · 0 0

Nope. You''re better off washing the scene down with chlorine bleach, which degrades DNA.

2006-09-12 23:49:59 · answer #8 · answered by I'm_Bored 4 · 0 0

There's no way that could happen. Your DNA is with you for the rest of your life.

2006-09-12 23:44:41 · answer #9 · answered by Lucy_Fir 3 · 0 0

That would be physically impossible.
You would have to have ALL your blood took out in order to do that,and you'd die without your blood.
Smart question though.

2006-09-12 23:51:56 · answer #10 · answered by lindsαy loserfαicee 2 · 0 0

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