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2006-09-09 18:19:03 · 7 answers · asked by Cammi 3 in Health Other - Health

7 answers

Non-Steroidal Anti-Inflammatory Drug (s)

Ibuprofen, naproxen, ketorolac, diclofenac, celecoxib (Celebrex), valdecoxib (Bextra, which is no longer available), rofecoxib (Vioxx, which is also no longer available) and, of course, the well-known tried and true beloved acetylsalicyclic acid--better known to the masses as aspirin.

So, how do NSAIDS work? We don't know for sure, but we do know that they inhibit the cyclooxygenase enzymes (both COX-1 and COX-2) which are responsible for, among other things, production of prostaglandins which play an important role in inflammation and pain (as well as fever). COX-2 more so than COX-1, I believe. (I don't remember the details--I tossed that information out after graduating from dental school!) The COX-1 enzyme, while involved with inflammation, also produces prostaglandins that promote adequate protective mucous lining of the stomach and it allows platelets to function.

Most NSAIDS affect both COX enzymes, however, some COX-2-selective NSAIDS have been developed (i.e. the "coxibs" I mentioned above), which have fewer GI and platelet side effects than aspirin and ibuprofen (non-selective COX inhibitors) have.

2006-09-09 18:32:39 · answer #1 · answered by Anonymous · 1 0

1

2016-09-03 03:50:27 · answer #2 · answered by Anonymous · 0 0

Non Steroidal Anti-Inflammatory Drugs (NSAIDs)

2006-09-09 18:25:16 · answer #3 · answered by kaliselenite 3 · 1 0

This Site Might Help You.

RE:
What does NSAIDS mean?

2015-08-18 05:48:55 · answer #4 · answered by Anonymous · 0 0

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Lower doses of NSAIDs, as recommended for use with nonprescription NSAIDs, are adequate to relieve pain in most people. To fully treat inflammation, a higher dose of the NSAID must be taken on a regular basis for several weeks before the full antiinflammatory benefit is realized. If the initial dose of NSAIDs does not improve symptoms, a clinician may recommend increasing the dose gradually or switching to another NSAID. People taking one NSAID should not take a second NSAID at the same time. NONSTEROIDAL ANTIINFLAMMATORY DRUG SIDE EFFECTS Most people tolerate NSAIDs without any difficulty. However, side effects can occur. The most common side effects include the following: •Gastrointestinal system — Short term use of NSAIDs can cause stomach upset (dyspepsia). Long term use of NSAIDs, especially at high doses, can lead to peptic ulcer disease and bleeding from the stomach. (See 'Ulcer disease' below.) •Liver toxicity — Long term use of NSAIDs, especially at high doses, can harm the liver. Monitoring the liver function with blood tests may be recommended in some cases. •Kidney toxicity — Use of NSAIDs, even for a short period of time, can harm the kidneys. This is especially true in people with underlying kidney disease. The blood pressure and kidney function should be monitored at least once per year, but may need to be checked more often, depending on a person’s medical conditions. (See 'Kidney disease' below.) •Ringing in the ears — Ringing in the ears (tinnitus) is common in people who take high doses of aspirin, although it can also occur in people who take other NSAIDs. The ringing usually resolves when the dose is decreased.

2016-04-01 20:19:41 · answer #5 · answered by Anonymous · 0 0

Just to add.
Tylenol IS NOT AN NSAID

2006-09-09 18:22:30 · answer #6 · answered by PreviouslyChap 6 · 0 0

What Does Nsaid Stand For

2016-09-30 03:11:00 · answer #7 · answered by hannula 4 · 0 0

non-steroidal.....oh whatever! yeah tylenol, panadol, aspirin-free excedrin are not nsaids, belong to a totally dif class of analgesics/antipyretic.

2006-09-09 18:25:08 · answer #8 · answered by Echo 4 · 0 0

non steroidal anti- inflammatory drugs... tylenol, motrin ext

2006-09-09 18:21:32 · answer #9 · answered by kpinette 3 · 1 0

http://www.chpa-info.org/ChpaPortal/PressRoom/FAQs/NSAIDs.htm

2006-09-09 18:25:36 · answer #10 · answered by Anonymous · 0 0

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