By the way you ask this question, I gather you are asking whether it results is COAGULATIVE or LIQUEFACTIVE necrosis.
Protein denaturation results in coagulative necrosis.
In coagulative necrosis, the tissue is turned into a solid, nonviable material. Think about an egg in the frying pan. Protein is heat-denatured and the egg white (mostly albumin) turns into a solid. The reason it turns solid is that the previously neatly folded protein chains are unfolded into long threads of amino acids which all tend to have the potential to interact with eachother in ionic and even covalent ways. The result is like taking a basket of yarn balls, unravelling them all and then throwing them back into the basket. It turns into one big tangled mess.
Liquefactive necrosis, on the other hand, happens as a result of chemical breakdown. For example when someone accidently (or on purpose) decides to drink lye (a severely alkaline fluid). This hydrolizes all sorts of chemical bonds including those within peptides and lipids. The result is that lots of little molecular fragments are left, and these do not have the tendency to form up a large solid. Hence the result is liquefaction of what used to be solid tissue!
2006-09-09 18:57:09
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answer #1
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answered by bellydoc 4
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All types of necrosis. That is the definition of necrosis.
APOPTOSIS or cell death in particular.
2006-09-09 17:38:55
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answer #2
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answered by PreviouslyChap 6
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