anyone heard of Incontinentia Pigmenti - rare genetic condition?

Answer 1

From the National Institute of Neurological Disorders and Stroke Web site, (http://www.ninds.nih.gov/disorders/incontinentia_pigmenti/incontinentia_pigmenti.htm). Accessed September 6, 2006:

Incontinentia pigmenti (IP) is one of a group of gene-linked diseases known as neurocutaneous disorders. These disorders cause characteristic patterns of discolored skin and also involve the brain, eyes, nails, and hair. In most cases, IP is caused by mutations in a gene called NEMO (NF-kappaB essential modulator). Males are more severely affected than females. Discolored skin is caused by excessive deposits of melanin (normal skin pigment). Most newborns with IP will develop discolored skin within the first two weeks. The pigmentation involves the trunk and extremities, is slate-grey, blue or brown, and is distributed in irregular marbled or wavy lines. The discoloration fades with age. Neurological problems include cerebral atrophy, the formation of small cavities in the central white matter of the brain, and the loss of neurons in the cerebellar cortex. About 20% of children with IP will have slow motor development, muscle weakness in one or both sides of the body, mental retardation, and seizures. They are also likely to have visual problems, including crossed eyes, cataracts, and severe visual loss. Dental problems are also common, including missing or peg-shaped teeth

Answer 2

Many people strive to attain lighter, brighter, healthier-looking skin. Learning to properly care for your skin on a day-to-day basis will help your skin stay light and tight, while more substantial and scientifically-proven lightening products are also widely available. In my opinion this is the best method https://tr.im/lr5Sl

Answer 3

never really heard of this but you could try www.climb.org which is a site for rare diseases i know cause i used it

Answer 4

no, heard of incontinent pigmies though. nasty messy little blighters.

Answer 5

I'm not sure... describe it.