Do you know someone that have the same characteristics of Edward Syndrome , but with no chromosome alteration?

Answer 1

I don't know anyone with Edwards Syndrome (trisomy 18) or with similar features.

emedicine considers the differential diagnosis to include:

Arthrogryposis

Fetal akinesia sequence
Mental retardation syndromes
Multiple congenital anomalies
Other autosomal trisomies and monosomies
Pseudo–trisomy 19 syndrome

Maybe the wikipedia will help