Fluoxetine is an antidepressant in a group of drugs called selective serotonin reuptake inhibitors (SSRIs). Fluoxetine affects chemicals in the brain that may become unbalanced and cause depression, panic, anxiety, or obsessive-compulsive symptoms.
• Fluoxetine is used to treat major depressive disorder, bulimia nervosa (an eating disorder) obsessive-compulsive disorder, panic disorder, and premenstrual dysphoric disorder (PMDD).
• Fluoxetine may also be used for purposes other than those listed in this medication guide.
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2006-08-25 07:44:45
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answer #1
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answered by noneofyourbizwax 3
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Fluoxetine hydrochloride is an antidepressant drug used medically in the treatment of depression, obsessive-compulsive disorder, bulimia nervosa, premenstrual dysphoric disorder and panic disorder. Fluoxetine is also used (off-label) to treat many other conditions, such as ADHD. Fluoxetine was derived from diphenhydramine, an antihistamine found to inhibit reuptake of the neurotransmitter serotonin.
Compared to other popular selective serotonin reuptake inhibitors (SSRIs), fluoxetine has a strong energizing effect. This makes fluoxetine highly effective in treatment of clinical depression cases where symptoms like depressed mood and lack of energy prevail. Although stimulating, it is also approved for a variety of anxiety disorders, including panic disorder and obsessive compulsive disorder.
Fluoxetine is sold under the brand names Prozac, Symbyax (compounded with olanzapine), Sarafem, FLUX (Pakistan), Fontex (Sweden), Foxetin (Argentina), Ladose (Greece), Fluctin (Austria, Germany), Prodep (India), Fludac* (India) Oxetin (Bosnalijek,Bosnia and Herzegovina), Seronil (Finland) and Lovan (Australia
Fluoxetine hydrochloride is approved in the United States to treat depression, obsessive-compulsive disorder, bulimia nervosa, premenstrual dysphoric disorder and panic disorder. In the United Kingdom, it is approved to treat depression with or without anxiety, bulimia nervosa, and obsessive-compulsive disorder.
In December 2003 the Food and Drug Administration (FDA) approved Symbyax to treat bipolar depression. Symbyax is a combination of fluoxetine and olanzapine. (However, the pure form of fluoxetine can cause mania, mixed-states, rapid cycling and psychosis in bipolar patients, particularly if the patient is not also taking a mood stabilizer.)
Common adverse effects include, akathisia, rage, anxiety, which is possibly associated with an interaction of fluoxetine with the pineal gland, in addition to restlessness and insomnia. Weight loss, trembling, weakness, skin rash, anorgasmia, itching, and a decrease in sexual drive, have also been reported. It has been reported to cause subsequent weight gain
Like other SSRIs, an overdose of fluoxetine or combining it with other antidepressants can lead to serotonin syndrome.
Studies and media reports have linked Prozac with increased incidences of homicide, suicide and reckless behavior
Fluoxetine is sold in capsules containing 10, 15, 20, 40, or 90 mg of active ingredient, in tablets containing 10 mg, or 20 mg or in an oral suspension with concentration of 20 mg/5 ml.
Prozac Weekly is 90 mg of regular enteric-coated fluoxetine, taken every 7 days. These capsules resist dissolution until reaching a segment of the gastrointestinal tract where the pH exceeds 5.5. The enteric coating delays the onset of absorption of fluoxetine 1 to 2 hours relative to the immediate-release formulations.
2006-08-25 08:00:10
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answer #2
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answered by Littlebigdog 4
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