What's ketamine?

Answer 1

Ketamine is a general dissociative anaesthetic for human and veterinary use. Its hydrochloride salt is sold as Ketanest®, Ketaset®, and Ketalar®. Pharmacologically it is very similar to other dissociative anesthetics such as tiletamine and phencyclidine (PCP).

Ketamine is a chiral compound, with two distinct enantiomers. Most pharmaceutical ketamine preparations are racemic, however reportedly some brands have (mostly undocumented) differences in enantiomeric proportions.

Ketamine was first synthesized in 1962 in an attempt to find a safer anaesthetic alternative to PCP, which was more likely to cause hallucinations and seizures. The drug was first used on American soldiers during the Vietnam War, but is often avoided now because it can cause potentially unpleasant out-of-body experiences. It is still used widely in veterinary medicine, and for select human applications.

Ketamine's side effects eventually made it a popular psychedelic in 1965. The drug was used in psychiatric and other academic research through the 1970s, culminating in 1978 with the publishing of John Lilly's The Scientist, a book documenting the author's ketamine, LSD, and isolation tank experiments. The incidence of recreational ketamine use increased through the end of the century, especially in the context of raves and other parties.

Since it suppresses breathing much less than most other available anaesthetics, ketamine is still used in human medicine as a first-choice anaesthetic for victims with unknown medical history (e.g. from traffic accidents), in podiatry and other minor surgery, and occasionally for the treatment of migraine. There is ongoing research in France, Russia, and the U.S. into the drug's usefulness in pain therapy and for the treatment of alcoholism and heroin addiction.

In veterinary medicine, ketamine is often used for its anaesthetic and analgesic effects on cats, dogs, rabbits, rats, and other small animals. Veterinarians often use ketamine with sedative drugs to produce balanced anaesthesia and analgesia, and as a constant rate infusion to help prevent pain wind-up. Ketamine is used to manage pain among horses and other large animals, though it has less effect on bovines.

Ketamine may be used in small doses (0.1–0.5 mg/kg/h) as an analgesic, particularly for the treatment of pain associated with movement and neuropathic pain. It has the added benefit of counter-acting spinal sensitization or wind-up phenomena experienced with chronic pain. At these doses, the psychotropic side effects are less apparent and well managed with benzodiazepines. Ketamine is a co-analgesic, requiring a concomitant low-dose opioid to be effective.

The effect of Ketamine as a depressant on the respiratory and circulatory systems is less than that of other anaesthetics. When used at anaesthetic doses, it will sometimes stimulate rather than depress the circulatory system. It is sometimes possible to perform ketamine anaesthesia without protective measures to the airways. Ketamine is also a potent analgesic and can be used in sub-anaesthetic doses to relieve acute pain; however, its psychotropic properties must be taken into account. Patients have reported going into other worlds or seeing God while anaesthetized, and these unwanted psychological side-effects have marginalized the use of ketamine in human medicine.

For more info see: http://en.wikipedia.org/wiki/Ketamine

Answer 2

Ketamine has actually been proposed as a therapeutic treatment for depression. It's early so I can't say anything about it. However I don't recommend doing it on your own time. One fun fact is the some studies suggest that diet and exercise are equally as effective as the leading medications. Without going deep into the mire of chemistry, if you eat junk food and stay home, it makes perfect sense to me that your brain would do the things it does in depression. For example, stress chemicals are released to just wake up in the morning. Not to mention if something is stressing you out. These chemicals are meant to make you run from the lion that is trying to eat you or beat the hell out of the guy stealing your baby. In the modern world when we get those chemicals at work or school, then go home and sleep, no wonder we are depressed, overweight and sickly. These chemicals have been shown to cause brain damage when built up too long, as well as opening the bodies defenses to illness and cancer. A process called excitotoxcixty makes schizophrenic people the way they are and causes you to lose brain tissue when you are depressed. Long story short if you are that into spending loads of money on drugs to feel better, why not get some depression medication? Sitting at home isn't going to make it better.

Answer 3

it's used as animal tranquilizer and also used as a general anesthetic sometimes in human surgery

i'm assuming you're asking because it came up somewhere someone using it recreationally. I can say beyond the shadow of a doubt, 100% that ketamine is one of the most dangerous drugs to OD on. It can kill you so easily it's not funny.

It suppresses heart rate, respirations, and blood pressure, ESPECIALLY taking it with other drugs or alcohol increases the liklihood of overdose by orders of magnitude...

hyperbole aside, it's a very good way to kill yourself

Answer 4

Horse Trancs

Answer 5

See links below

Its basically field surgery and horse tranquilizer that separates mind from body often paralysing you or causing you to loose control of your body and hallucigenic. Unlike LSD often you can't be convinced the hallucinations are fake if you are having a bad trip which can make it a lot worse.
Likewise choking on vomit is more likly which can be fatal if you can t moove.

Often used as a cheaper filler in ecstacy.

As a tranqillier very dangerous to mix with alcohol

Meant for injecting you when they have to cut off your arm to get you out of a car wreck.

http://www.drugscope.co.uk/druginfo/drugsearch/ds_results.asp?file=\wip\11\1\1\ketamine.html

Common in rave or gay circles.

www.drugscope.co.uk

http://www.lifeline.org.uk/
http://www.lifeline.org.uk/help.asp
http://www.lifelinepublications.org/catalogue2.php?catid=R8
This is the booklet on ketamine

Lifeline producing the best info leaftlets etc in a fun clubber way designed by ex clubber and their info comes from drugscope formally the ISDD

http://talktofrank.com/
http://talktofrank.com/azofdrugs/K/Ketamine.aspx

I have listed the best info sources in thye uk ask them not here...

That way you get accurate info and don't worry you cn ask what you want they wont dop you in to the cops or lie to you.


Where as asking your mates or here you dont dont whats true and whats bollocks

Answer 6

I saw someone given ketamine, shortly before a lumbar puncture.
the doctor barely counted to 7 (seconds) and she was unconcious.

Answer 7

It is used to tranquilise horses and is often taken as a drug by humans as it creates a 'high'.

Answer 8

Ketamine is a general dissociative anaesthetic for human and veterinary use. Its hydrochloride salt is sold as Ketanest®, Ketaset®, and Ketalar®. Pharmacologically it is very similar to other dissociative anesthetics such as tiletamine and phencyclidine (PCP).

Answer 9

Ask your doctor about an exercise routine. Regular exercise, such as walking three times a week, may reduce neuropathy pain, improve your muscle strength and help control blood sugar levels. Gentle routines such as yoga and tai chi might also help.

Answer 10

It's a chemical that people put in Ecstasy...think it's an animal tranquiliser really?