The sedimentation rate (sed rate) blood test measures how quickly red blood cells (erythrocytes) settle in a test tube in one hour.
When inflammation is present in the body, certain proteins cause red blood cells to stick together and fall more quickly than normal to the bottom of the tube. The more red cells that fall to the bottom of a special test tube in one hour, the higher the sed rate. These proteins are produced by the liver and the immune system under many abnormal conditions, such as an infection, an autoimmune disease, or cancer. There are many possible causes of an elevated sedimentation rate. For this reason, a sed rate is done with other tests to confirm a diagnosis. Once a diagnosis has been made, a sed rate can be done to help monitor the course of the disease or the effectiveness of treatment.
A high sedimentation rate (sed rate) may indicate inflammation caused by an infection. Infections may include:
-Pneumonia.
-Pelvic inflammatory disease.
-Appendicitis.
-Kidney, bone, joint, skin, or heart valve infections.
-A high sed rate may also indicate some types of cancer (especially lymphoma or multiple myeloma), an autoimmune disease (such as systemic lupus erythematosus), certain inflammatory diseases (such as rheumatoid arthritis or polymyalgia rheumatica) or other medical conditions (such as chronic kidney failure, toxemia of pregnancy, or thyroid disease).
An extremely high sed rate (greater than 100 mm/hr) is often found in some severe infections (such as osteomyelitis or endocarditis), certain inflammatory diseases (such as temporal arteritis), and certain types of cancer (such as multiple myeloma or lymphoma).
2006-08-20 03:46:04
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answer #1
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answered by hello 4
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There many causes of high ESR most important is infection and rheumatic disease .
2006-08-20 02:55:02
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answer #2
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answered by Fouad 3
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Please see the webpages for more details on Erythrocyte Sedimentation Rate.
2006-08-19 19:13:08
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answer #4
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answered by gangadharan nair 7
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