can one predict the possible harmful effects of drugs on human embryo from studies performed on animals?

Answer 1

Well, it's always hard to be sure.

However, because embryonic development in mammals, particularly early on, is very similar - almost identical genes are switched on at various times to control development - I would imagine that you would be able to make firm conclusions on embryo toxicity from drug studies on animals than you would on studies on adult animals, where the anatomy and physiology will be significantly different.

Answer 2

Not always.

If something causes teratogenicity in lab animals, it's important to first check the concentration of the drug the animal was exposed to. In many studies, they use several times the concentration that a human would actually be exposed to.

However, even if large concentrations are used and they do cause harm, one wouldn't want to test it in human women who were pregnant. The information can be useful in counseling a pregnant woman exposed to the drug.

There have also been a few drugs that did NOT cause harm to lab animals, but did cause harm to human embryos...so even animal testing is not 100%.

Answer 3

All 'non secular sentiments' aside, i individually discover it abhorrant, repulsive, unnatural, and want not something regardless of to do with it or any of its outcomes. We, regardless of creed, coulour, race, are human - animals of the animal international are in simple terms that. In nature, species do not mate to create hybrids, and there is nice rationalization for that. think of being a 'hybrid' toddler, allowed to become a toddler - and you in basic terms know there is somebody accessible interior the medical international which will take this step. you have the physique of regardless of animal your genes have been spliced with, however the ideas of a human - or a physique that's a actual blend of the two. What torture that is by using fact the toddler develops and realises that, not in basic terms is it a prisoner in a lab someplace with in basic terms the human 'kindness' of the scientists that developed it to count upon, however the insanity that it may experience as quickly because it realises why that's what that's. How inhuman is that? i won't understand the character of the ideas that could use ability human beings for such evil acts. As different replies have stated, lots of the incorrect issues in this international are the consequence of experimentation interior the call of progression. whilst they have been given the ok for this, it may be yet another small push for added experimentation and progression of our nightmares.