Does anyone know what???

Question

what is neurofibromatosis and how does it effect people, I suffer from it but know little about it, Many thx

Answer 1

I have neurofibromatosis too, so does my sister and my late mother had it, I know little of it..try looking it up in a serach engine i might do that to cos I know little about it.

Answer 2

I have not really studied it, but according to Tabers Cyclopedic Medical Dictionary:

neurofibromatosis (nÅ«″rō-fÄ«-brō″mă-tō′sÄ­s) [″ + ″ + ″ + osis, condition] A group of genetic disorders that affects the cell growth of neural tissues. A characteristic of the disease is the growth of neurofibromas in many locations within or on the surface of the body. For those persons with affected family members, genetic assessment and counseling of parents may be indicated. Genetic assessment and counseling can identify the parents' risk of being a gene carrier and passing the disease on to subsequent offspring. SEE: illus.
type 1 neurofibromatosis (NF-1) An autosomal dominant disease that affects about 1 in 3000 persons. Its clinical hallmarks include hyperpigmented macules on the skin (café au lait spots) and multiple cutaneous and subcutaneous tumors that appear in late childhood (there may be only a few or thousands). When the tumors are pressed, they pass through a small opening in the skin, leaving the space previously occupied vacant. This characteristic, called buttonholing, helps to distinguish these tumors from lipomas. In about 2% to 5% of cases, the tumors become malignant. No cure has yet been found. Tumors that give rise to symptoms or those that become malignant should be excised; however, if the tumor is on a vital nerve, excision may be impossible. Radiation therapy and surgery are of benefit. SYN: Recklinghausen's disease
type 2 neurofibromatosis (NF-2) An autosomal dominant disease, affecting 1 in 50,000 persons, that causes intracranial and spinal tumors, esp. of the eighth cranial nerve. Although the disease is incurable, its symptoms can be palliated with multidisciplinary care.

Copyright 2005 by F. A. Davis Company

Answer 3

Neurofibromatosis is an autosomal dominant genetic disorder. It encompasses a set of distinct genetic disorders that cause tumors to grow along types of nerves and, in addition, can affect the development of non-nervous tissues such as bones and skin. The tumors can grow anywhere on or in the body

Answer 4

It is a genetic disorder (passed from parents) that affects cell growth of neural tissues. There appears to be many hyperpigmented areas (dark spots on the skin) with multiple small tumors just below the skin surface. The tumors only become cancerous in 2-5% of all patients, and there is no know cure.

Answer 5

Please see the webpages for more details on Neurofibromatosis.