Although LSD is generally considered nontoxic, it may temporarily impair the ability to make sensible judgments and understand common dangers, thus making the user susceptible to accidents and personal injury.
There is also some indication that LSD may trigger a dissociative fugue state in individuals who are taking certain classes of antidepressants such as lithium salts and tricyclics. In such a state, the user has an impulse to wander, and may not be aware of his or her actions, which can lead to physical injury.[26] SSRIs are believed to interact more benignly, with a tendency to noticeably reduce LSD's subjective effects.[27] Similar and perhaps greater reductions have also been reported with MAOIs.[26]
As Albert Hofmann reports in LSD – My Problem Child, the early pharmacological testing Sandoz performed on the compound (before he ever discovered its psychoactive properties) indicated that LSD has a pronounced effect upon the mammalian uterus. Sandoz testing showed that LSD can stimulate uterine contractions with efficacy comparable to ergobasine, the active uterotonic component of the ergot fungus. (Hofmann's work on ergot derivatives also produced a modified form of ergobasine which became a widely accepted medication used in obstetrics, under the trade name Methergine.) LSD use by pregnant women is therefore contraindicated.[3]
Initial studies in the 1960s and 70s raised concerns that LSD might produce genetic damage or developmental abnormalities in fetuses. However, these initial reports were based on in vitro studies or were poorly controlled and have not been substantiated. In studies of chromosomal changes in human users and in monkeys, the balance of evidence suggests no significant increase in chromosomal damage. For example, studies were conducted with people who had been given LSD in a clinical setting.[28] White blood cells from these people were examined for visible chromosomal abnormalities. Overall, there appeared to be no lasting changes. Several studies have been conducted using illicit LSD users and provide a less clear picture. Interpretation of these data is generally complicated by factors such as the unknown chemical composition of "street" LSD and concurrent use of other psychoactive drugs. It seems possible that the small number of congenital abnormalities reported in users of street LSD is either coincidental or related to factors other than a toxic effect of pure LSD.
2006-08-06 12:00:44
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answer #1
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answered by ? 3
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Hi Officer MM
2006-08-06 19:01:16
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answer #2
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answered by Anonymous
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You evidently must be on LSD now to ask this question on here.
2006-08-07 02:36:08
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answer #3
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answered by COOKIE 5
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I think that Adam 91 was trying to say.... No, I don't have a hook-up.
Bold and stupid question to be asking in a public forum!
2006-08-06 19:04:16
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answer #4
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answered by and,or,nand,nor 6
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You mean, Lake Shore Drive? (I sure hope so.) That's in Chicago.
2006-08-06 23:04:37
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answer #5
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answered by mrschrisc 2
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I dont get it, drugs in general..why would you waste your life on doing that stuff, you only get one, why waste it? waste of time, waste of life, waste of money....
2006-08-06 23:00:37
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answer #6
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answered by xtina51279 1
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