what is the working principle of serotonin,a neurotransmitter in brain?

Answer 1

In the central nervous system, serotonin is believed to play an important role in the regulation of mood, sleep, emesis (vomiting), sexuality and appetite. Serotonin has been thought to play a part in many disorders, notably as part of the biochemistry of depression, migraine, bipolar disorder and anxiety. Recent research suggests that serotonin also plays an important role in liver regeneration and acts as a mitogen (induces cell division) throughout the body.[1]

Answer 2

NOUN:

An organic compound, C10H12N2O, formed from tryptophan and found in animal and human tissue, especially the brain, blood serum, and gastric mucous membranes, and active as a neurotransmitter and in vasoconstriction, stimulation of the smooth muscles, and regulation of cyclic body processes.

Remarkably only 2% of the total body's serotonin is in the brain, although it activity in the brain that is affected by psychiatric medication. Elsewhere it is found in the cells of the gut and blood cells.

Serotonin is a neurotransmitter. This means it is the chemical link between brain cell neurones. It is not the only neurotransmitter in the brain and is found in neuronal pathways particularly in the brainstem and midbrain.

It has been suggested that neurones that use serotonin as a transmitter are involved in coping responses to acute and chronic aversive events. It is this that has produced the view that serotonin is involved in the causes of depressive illness.

I am sorry if this sounds complicated. In fact it is vastly more complicated still, but I hope my simplification helps a little.

Answer 3

It depends on what you mean by working principle. Although it is important to note that 5-HT (serotonin) is not the feel-good chemical in your brain that it is always made out to be (That fact was hammered into our heads in a neuroscience class i took).