What is the difference between Hydrocodone and Oxycodone?

Question

Are they different mechanisms? Can they be taken together, possibly alternating from one to the other every six hours?

Answer 1

Hydrocodone:
Hydrocodone or dihydrocodeinone (marketed as Vicodin, Anexsia, Dicodid, Hycodan, Hycomine, Lorcet, Lortab, Norco, Hydroco, Tussionex, Vicoprofen) is an opioid derived from either of the naturally occurring opiates codeine or thebaine. Hydrocodone is an orally active narcotic analgesic and antitussive. Sales and production of this drug have increased significantly in recent years, as have diversion and illicit use. Hydrocodone is commonly available in tablet, capsule and syrup form.
As a narcotic, hydrocodone relieves pain by binding to opioid receptors in the brain and spinal cord. It may be taken with or without food. When taken with alcohol, it can intensify drowsiness. It may interact with monoamine oxidase inhibitors, as well as other drugs that cause drowsiness. It is in FDA pregnancy category C: its effect on an embryo or fetus is not clearly known and pregnant women should consult their physicians before taking it. Common side effects include dizziness, lightheadedness, nausea, drowsiness, euphoria, vomiting, and constipation. Some less common side effects are allergic reaction, blood disorders, changes in mood, mental fogginess, anxiety, lethargy, difficulty urinating, spasm of the ureter, irregular or depressed respiration and rash.

Hydrocodone can be habit-forming , and can lead to physical and psychological addiction. In the U.S., pure hydrocodone and forms containing more than 15 mg per dosage unit are considered Schedule II drugs. Those containing less than or equal to 15 mg per dosage unit in combination with acetaminophen or another non-controlled drug are called Hydrocodone Compounds and are considered Schedule III drugs. Hydrocodone is typically found in combination with other drugs such as paracetamol (acetaminophen), aspirin, ibuprofen and homatropine methylbromide. The purpose of the non-controlled drugs in combination is often twofold. 1) To provide increased analgesia via drug synergy. 2) To limit the intake of hydrocodone by causing unpleasant and often unsafe side effects at higher than prescribed doses (See Below). In the UK it is listed as a Class A drug under the Misuse of Drugs Act 1971.



Oxycodone:
Oxycodone is a very powerful and addictive opioid analgesic medication synthesized from thebaine.

It is effective orally and is marketed in combination with aspirin (Percodan, Endodan, Roxiprin) or paracetamol (Percocet, Endocet, Roxicet, Tylox) for the relief of pain. More recently, ibuprofen has been added to oxycodone (Combunox). It is also sold in a sustained-release form by Purdue Pharma under the trade name OxyContin as well as generic equivalents, and instant-release forms Endone, OxyIR, OxyNorm, Percolone, OxyFAST, and Roxicodone. Roxicodone is available in 5, 15, and 30 mg tablets. OxyContin is available in 10, 20, 40, and 80 mg tablets, and, due to its sustained-release mechanism, is effective for eight to twelve hours. (The 160 mg formulation was discontinued in May 2001.) OxyNorm is available in 5, 10, and 20 mg capsules and tablets; also as a 1 mg/1 ml liquid in 250 mg bottles and as a 10 mg/1 ml concentrated liquid in 100 mg bottles.

In the United States, oxycodone is a Schedule II controlled substance both as a single agent and in combination products containing paracetamol, ibuprofen or aspirin.

Good Luck.

Answer 2

Hydrocodone is the active ingredient in Vicodin and Lortab. They can be either 5 or 7.5 mg and are combined with acetaminophen (tylenol). Oxycodone is the active ingredient in Percodan (with aspirin) or Percocet (with tylenol). It is also available in a timed release medication called Oxycontin (not mixed with any other medication). Oxycodone is usually considered to be stronger than hydrocodone, but different people react to them in different ways. Codeine is an older and milder drug than either of the other two. It usually comes in #2, #3 and #4--15, 30 and 60 mg respectively. All of these drugs are narcotics, are addictive and should not be taken unless prescribed by a physician. People get addicted to these drugs and build up a tolerance to them. When they start out, one makes them feel good. It gets to where it takes 5 just to get going every day, and they don't make you feel good anymore. And all that tylenol and aspirin can kill you slowly.

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Answer 3

OxyContin (oxycodone HCI controlled-release) is the brand name for an opioid analgesic (pain reliever) -- a narcotic. It is available by prescription only and is used to treat moderate to severe pain when around-the-clock analgesic is needed for an extended period of time.


What does it look like?
OxyContin is available in tablet form in 5 doses: 10, 20, 40, 80, and 160mg. (However, the manufacturer is no longer shipping 160mg).
How is it used?
As pain medication, OxyContin is taken every 12 hours because the tablets contain a controlled, time-release formulation of the medication. Most pain medications must be taken every three to six hours. Oxycontin abusers remove the sustained-release coating to get a rapid release of the medication, causing a rush of euphoria similar to heroin.
What are its short-term effects?
The most serious risk associated with opioids, including OxyContin, is respiratory depression. Common opioid side effects are constipation, nausea, sedation, dizziness, vomiting, headache, dry mouth, sweating, and weakness. Taking a large single dose of an opioid could cause severe respiratory depression that can lead to death.
What are its long-term effects?
Chronic use of opioids can result in tolerance for the drugs, which means that users must take higher doses to achieve the same initial effects. Long-term use also can lead to physical dependence and addiction -- the body adapts to the presence of the drug, and withdrawal symptoms occur if use is reduced or stopped.Properly managed medical use of pain relievers is safe and rarely causes clinical addiction, defined as compulsive, often uncontrollable use of drugs. Taken exactly as prescribed, opioids can be used to manage pain effectively.


Hydrocodone


Hydrocodone is an effective antitussive (anti-cough) agent, and as an opiate it is also an effective analgesic for mild to moderate pain control. Five mg of hydrocodone is equivalent to 30 mg of codeine when administered orally. Early comparisons concluded that hydrocodone and morphine were equipotent for pain control in humans. However, it is now considered that a dose of 15 mg (1/4 gr) of hydrocodone is equivalent to 10 mg (1/6 gr) of morphine. Hydrocodone is considered to be morphine-like in all respects.

There are over 200 products containing hydrocodone in the U.S. In its most usual product forms hydrocodone is combined with acetaminophen (Vicodin, Lortab), but it is also combined with aspirin (Lortab ASA), ibuprofen (Vicoprofen), and antihistamines (Hycomine). Both tablet and liquid forms of hydrocodone are available (e.g., Tussionex)

Hydrocodone is in Schedule II of the Controlled Substances Act. Preparations containing hydrocodone in combination with other non-narcotic medicinal ingredients are in Schedule III.

Vicodin, hydrocodone in combination with acetaminophen, is a commonly abused version of hydrocodone. Vicodin, as with all narcotic analgesics, can be habit forming---causing dependence, tolerance, and withdrawal symptoms if not used as it is prescribed.
i would not recomend to be taken both in the same time ,but ask your doc about your specific indications and use advice

Answer 4

The former is a hydrogen based compound, the latter is an oxygen based compound

Answer 5

You expect to get a serious answer from this question?? You are asking it on YAHOO Mr. Brain Surgeon

Answer 6

Check www.drugdigest.com for detailed and specific info related to those meds :)

Answer 7

Hydrocodone
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Hydrocodone and Ibuprofen (Systemic) Hydrocodone and ibuprofen (hye-droe-KOE-done and eye-byoo-PROE-fen) combination is used to relieve pain.
Narcotic Analgesics and Acetaminophen (Systemic) Combination medicines containing narcotic analgesics(nar-KOT-ik an-al-JEE-zicks)and acetaminophen (a-seat-a-MIN-oh-fen) are used to relieve pain. A narcotic analgesic and acetaminophen used together may provide better pain relief than either ...
Narcotic Analgesics and Aspirin (Systemic) Combination medicines containing narcotic analgesics(nar-KOT-ik an-al-JEE-zicks)and aspirin (AS-pir-in) are used to relieve pain. A narcotic analgesic and aspirin used together may provide better pain relief than either medicine used alone. In some ...
Narcotic Analgesics— For Pain Relief (Systemic) Narcotic (nar-KOT-ik) analgesics (an-al-JEE-zicks) are used to relieve pain. Some of these medicines are also used just before or during an operation to help the anesthetic work better. Codeine and hydrocodone are also used to relieve coughing.

Oxycodone
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Ibuprofen and Oxycodone (Systemic) Ibuprofen and oxycodone (eye-byoo-PROE-fen and ox-i-KOE-done) combination is used to relieve pain.
Narcotic Analgesics and Acetaminophen (Systemic) Combination medicines containing narcotic analgesics(nar-KOT-ik an-al-JEE-zicks)and acetaminophen (a-seat-a-MIN-oh-fen) are used to relieve pain. A narcotic analgesic and acetaminophen used together may provide better pain relief than either ...
Narcotic Analgesics and Aspirin (Systemic) Combination medicines containing narcotic analgesics(nar-KOT-ik an-al-JEE-zicks)and aspirin (AS-pir-in) are used to relieve pain. A narcotic analgesic and aspirin used together may provide better pain relief than either medicine used alone. In some ...
Narcotic Analgesics— For Pain Relief (Systemic) Narcotic (nar-KOT-ik) analgesics (an-al-JEE-zicks) are used to relieve pain. Some of these medicines are also used just before or during an operation to help the anesthetic work better. Codeine and hydrocodone are also used to relieve coughing.