Pernicious anemia (an "enema" is a whooooole other thang!) is caused by a deficit of a substance called "intrinsic factor," which is a substance your body needs in order to absorb vitamin B-12 from the gastrointestinal tract. This deficit can be caused by chronic gastritis (intrinsic factor is made by cells in the stomach -- damage the cells and they can't make it anymore) or as the result of surgery to remove the stomach. Very rarely, it is a congenital condition (you're born with it).
Without enough B-12, your body can't make enough red blood cells. This condition is usually not diagnosed in people until middle age. Symptoms include shortness of breath, fatigue, pale skin, rapid heart rate, loss of appetite, diarrhea, tingling in the extremities, unsteady gait, impaired sense of smell, an sometimes personality changes. The neurological effects (tingling, unsteady gait, e.g.) can sometimes be seen well before the anemia is even diagnosed.
Treatment typically involves monthly B-12 injections, which can correct the anemia and correct any neurological complications if given soon enough. Sometimes doctors also recommend that patients take oral B-12 supplements in addition to the monthly injections (typically advised for elderly patients with gastritis).
Vitamin B-12 has a very low potential for toxicity, so there's no need to worry about getting too much of it.
2006-07-28 14:17:48
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answer #1
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answered by Meg 5
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Vitamin B12 deficiency is characterized by abnormally low levels of circulating B12 due to a poor diet or inadequate absorption of this vitamin by the stomach. Unlike pernicious anemia, people with Vitamin B12 deficiency typically have normal levels of intrinsic factor. Most people with the disorder have abnormally low red blood cell counts (anemia). Symptoms may include an abnormally enlarged spleen or liver, lack of appetite, intermittent constipation and diarrhea, and/or abdominal pain. This deficiency is very rare due to storage of vitamin B12 in the liver that lasts for 3 to 5 years. When insufficient B12 is in the diet, the liver releases B12 to compensate for the loss.
I believe the body 'dumps' the excess. This is something best discussed with your Dr.
2006-07-28 14:12:05
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answer #2
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answered by scgleason74 3
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Hi there, I agree with what Meg said but have to add to it. My father is a WW2 veteran, he has had pernicious anemia for almost 70 years, he's had all sorts of treatments, used to go in for transfusions every single year! B12 will help but you can also get an over the counter vitamin now that will help you alot. Slow Fe extended release iron. He's been on that for the last 4 years and it has worked wonders. He gets a periodic B12 shot to boost him but the vitamin has done what surgeries, transfusions and more has not, slowly kept iron in his system to complement other resources from his own body and foods.
2006-07-28 15:36:22
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answer #3
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answered by Tina of Lymphland.com 6
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I believe you mean pernicious anemia, an enema is where you inject fluid into the rectum to relieve constipation.
2006-07-29 18:11:19
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answer #4
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answered by wetsaway 6
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26. Prostitutes continuously appear as if Julia Roberts or Jamie Lee Curtis. they have costly clothing and large apartments yet no pimps. they are friendly with the shopkeepers of their neighbourhood who don`t ideas in any respect what the female does for a residing.
2016-10-01 05:12:54
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answer #5
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answered by manjeet 4
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try wikipedia
2006-07-28 14:12:33
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answer #6
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answered by ? 6
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