elevated immunoglobulin A?

Question

what does an elevated immunoglobulin A mean?

Answer 1

Increased levels of IgA can indicate chronic liver disease, chronic infections, or inflammatory bowel disease.
Increased monoclonal IgA may be produced in lymphoproliferative disorders, especially multiple myeloma and "Mediterranean" lymphoma involving bowel. An IgA monoclonal peak >2 g/dL is a major criterion for myeloma. It may be elevated in a wide range of conditions affecting mucosal surfaces, where IgA is largely produced.
IgA constitutes approximately 15% of the immunoglobulins within the body. Although it is found to some degree in the blood, it is present primarily in the secretions of the respiratory and gastrointestinal tract, in saliva, colostrum (the yellowish fluid produced by the breasts during late pregnancy and the first few days after childbirth), and in tears. IgA plays an important role in defending the body against invasion of germs through the mucous membrane-lined organs.

So your doctor should interpret the result of Ig A level and use the clinical presentation to come up with the possible diagnosis. Further testing is likely necessary.

Answer 2

Elevated levels of secretory immunoglobulin A (sIgA) in urinary tract infections. Elevated levels of secretory immunoglobulin A (sIgA) in urinary tract infections. www.ijppediatricsindia.org/article.asp?issn=0019