How fatal is nephrotic syndrome?

Question

How many years would it take to loose kidney function

Answer 1

Nephrotic syndrome is a condition marked by very high levels of protein in the urine; low levels of protein in the blood; swelling, especially around the eyes, feet, and hands; and high cholesterol. Nephrotic syndrome results from damage to the kidneys' glomeruli (the singular form is glomerulus). Glomeruli are tiny blood vessels that filter waste and excess water from the blood and send them to the bladder as urine.

Nephrotic syndrome can occur with many diseases, including the kidney diseases caused by diabetes mellitus, but some causes are unknown. Prevention of nephrotic syndrome relies on controlling these diseases.

Treatment of nephrotic syndrome focuses on identifying the underlying cause if possible and reducing high cholesterol, blood pressure, and protein in urine through diet, medications, or both. One group of blood pressure medications called ACE inhibitors also protects the kidneys in diabetic patients.

Nephrotic syndrome may go away once the underlying cause, if known, has been treated. However, most of the time a kidney disease is the underlying cause, and these diseases cannot be cured. In these cases, the kidneys may gradually lose their ability to filter wastes and excess water from the blood. If kidney failure occurs, the patient will need dialysis or a kidney transplant.

Prognosis depends on the underlying disorder. Minimal change disease has the best prognosis of all the kidney disorders, with 90% of all patients responding to treatment. Other types of kidney diseases have less favorable outcomes, with high rates of progression to kidney failure. When nephrotic syndrome is caused by another, treatable disorder (infection, allergic or drug reaction), the prognosis is very good.

Answer 2

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Answer 3

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How fatal is nephrotic syndrome?
How many years would it take to loose kidney function

Answer 4

The prognosis varies depending on the cause of the nephrotic syndrome, your age, and the type and degree of kidney damage. Symptoms may disappear completely if the nephrotic syndrome is caused by a treatable disorder, such as an infection, cancer, or drugs. This situation occurs in about half the cases in children but less often in adults. If the underlying disorder responds to corticosteroids, sometimes progression of the disease is halted, and less often the condition partially, or rarely, completely reverses. When the syndrome is caused by HIV infection, it usually progresses relentlessly, often resulting in complete kidney failure in 3 or 4 months. Children born with the nephrotic syndrome rarely live beyond their first birthday, although a few have survived by means of dialysis treatments or a kidney transplant. When the cause is systemic lupus erythematosus or diabetes mellitus, treatment with an angiotensin-converting enzyme (ACE) inhibitor often stabilizes or decreases the amount of protein in the urine. However, some people do not respond to treatment with an ACE inhibitor and develop progressive kidney failure within a few years. In cases of nephrotic syndrome resulting from conditions such as an infection, allergy, or intravenous heroin use, the prognosis varies, depending on how early and effectively the underlying condition is treated.

Answer 5

According to a couple of website I have found, much of it depends on why it appeared. It is almost always caused by someting else. If it is due to something that is cureable, it may go away. Otherwise, for something like diabetes, it may eventually end in kidney failure. When is a matter of how well you are keeping your protein from building up in your urine, which there are some drugs for.

Answer 6

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My husband has Minimal Change (onset age 14, age 40 now - so he is definitely not typical). We have tried several things over the years, but unfortunately the only thing that keeps him in remission is a low daily dose of cyclosporin. He also takes Cozaar and Zetia to support the cyclopsorin. Good luck!

Answer 7

I can only tell of allopathy. The causes and the pathogenesis (how the disease starts)of Minimal change disease is still not known hence the treatment being given is only symptomatic and for suppressing the disease process. Steroids are given however in the later stages other stronger drugs (such as cytotoxic drugs) have to be resorted to. Of course, finally they develop renal failure. With the above mode of treatment 10 year survival rate is above 90%. Cheers!!!

Answer 8

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Answer 10

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