Apart from increased release from damaged cells, why would blood enzyme levels be increased?

Question

I need to write about at least 3 other mechanisms by which enzyme activity in blood would increase, that would not be due to increased release from damaged or diseased tissues, but could be due to disease or toxicity. Im finding it hard to find sources on the internet, does anyone know of any websites that may help? Thanks

Answer 1

Enzyme levels can also be increased by

Perceived or immediate threats

Sexual activity

Ingestion and Digestion of food.

Answer 2

Enzymes from the liver can be increased by alcohol, and many drugs. As the liver works hard to clear the body of drugs, it produces more of the necessary enzymes and so you see more in the blood.

Many bone diseases increase an enzyme called alkaline phosphatase (ALP). There are cells that break down bone and form new bone and when they are more active then they release lots more ALP. This happens with conditions like calcium deficiency and Paget's disease.

Some enzymes are affected by age, sex or ethnicity. For example ALP is raised in children when they're growing fast. CK (creatine kinase) is higher in men and black people (more muscle mass).

Answer 3

Like the first person said - digestive enzymes would be released - but the first thing that springs to mind are enzymes involved in the release of reactive oxygen and nitrogen species (free radicals) such as nitric oxide synthase, superoxide dismutase and NAPDH oxidase, which are released by healthy cells especially certain white blood cells, during infection. There are also lots of other anti-microbial enzymes.

Answer 4

why not pregnancy;)?