What does low lipase level indicate?

Question

I read that if you have high lipase levels one may have pancreatitis. What if levels are lower than normal? What does it indicate? Help me with my homework, I can't seem to find the answer in my books, all they say is elevated levels but none of the low. Thanks ^_^

Answer 1

Eh, low lipase levels means that you do not have enough enzymes to digests lipids, which may result in diabetes as insulin metabolism is interefered with and insulin’s transport of glucose into the cells is lessened. They might have high cholestrol, inablilty to digest fat, difficulity with losing weight and high blood pressure.

Answer 2

Lipase Levels

Answer 3

Among the possibilities: Cystic Fibrosis, also Low lipase levels may indicate that there might be a permanent damage to the lipase producing cells in the pancreas. As well as inability to absorb vitamins and process fat and can cause diabetes.

Answer 4

Low lipase in serum should be normal. High lipase - suspicious for pancratitis and many other conditions

Why get tested?
To diagnose pancreatitis or other pancreatic disease

When to get tested?
If you have symptoms of a pancreatic disorder, such as severe abdominal pain, fever, loss of appetite, or nausea

Sample required?
A blood sample drawn from a vein in the arm

This is a blood test to measure the amount of the enzyme lipase.

How the test is performed

Blood is drawn from a vein on the inside of the elbow or the back of the hand. The puncture site is cleaned with antiseptic, and an elastic band is placed around the upper arm to apply pressure and restrict blood flow through the vein. This causes veins below the band to fill with blood.

A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. During the procedure, the band is removed to restore circulation. Once the blood has been collected, the needle is removed, and the puncture site is covered to stop any bleeding.

For an infant or young child, the area is cleansed with antiseptic and punctured with a sharp needle or a lancet. The blood may be collected in a pipette (small glass tube), on a slide, onto a test strip, or into a small container. Cotton or a bandage may be applied to the puncture site if there is any continued bleeding.

How to prepare for the test

Fast for 8 hours before the test. The health care provider may advise you to stop taking drugs that may affect the test (see special considerations).

For infants and children:

The preparation you can provide for this test depends on your child's age and experience. For specific information regarding how you can prepare your child, see the following:
http://www.labtestsonline.or
http://www.symptomat.com
http://www.rdoctor.com
http://www.nlm.nih.gov/medlineplus


At least three human genetic diseases are caused by mutations in lipase genes. Lipoprotein lipase deficiency is caused by mutations in the gene encoding lipoprotein lipase [1]. Cholesteryl Ester Storage Disease (CESD) and Wolman Disease are both caused by mutations in the gene encoding lysosomal lipase, also referred to as lysosomal acid lipase (LAL or LIPA) or acid cholesteryl ester hydrolase [2].


Lipases are ubiquitous throughout living organisms, and genes encoding lipases are even present in certain viruses. While a diverse array of genetically distinct lipase enzymes are found in nature, and represent distinct types of protein folds and catalytic mechanisms, most are built on an alpha/beta hydrolase fold (see image) and employ a chymotrypsin-like hydrolysis mechanism involving a serine nucleophile, an acid residue (usually aspartic acid), and a histidine.

Answer 5

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RE:
What does low lipase level indicate?
I read that if you have high lipase levels one may have pancreatitis. What if levels are lower than normal? What does it indicate? Help me with my homework, I can't seem to find the answer in my books, all they say is elevated levels but none of the low. Thanks ^_^

Answer 6

Low lipase level has absolutely no significance medically. When they set up a "normal range" for medical results, about 5 - 10% of people fall above and below that range. It is like saying a man is only 5 feet tall, he is below the normal range but that does not affect his health. Don't worry. You are normal!

Answer 7

Low lipase shouldn't be a problem, i get pancreatitis when my levels are high so i wouldn't worry about it being to low.

Answer 8

Pancreatic Lipase (steapsin)-a fat splitting enzyme produced by pancreas. It splits fat into fatty acids and glycerine.
Please see the webpages on Pancreatitis, Acute Pancreatitis, Chronic pancreatitis, and Secretin stimulation test.

Answer 9

I agree with much of what smashingly.smashing answered; but I believe the true answer to this question is simple...cycstic fibrous.