(m)
Parkinson's disease (paralysis agitans or PD) is a movement disorder often characterized by muscle rigidity, tremor, a slowing of physical movement (bradykinesia), and in extreme cases, a loss of physical movement (akinesia). The primary symptoms are due to excessive muscle contraction, normally caused by the insufficient formation and action of dopamine, which is produced in the dopaminergic neurons of the brain. Parkinson's disease was first formally recognised and its symptoms documented in 1817 in An Essay on the Shaking Palsy by the British physician Dr James Parkinson; the associated biochemical changes in the brain of patients were identified in the 1960s.
Parkinson disease affects movement (motor symptoms). Typical other symptoms include disorders of mood, behavior, thinking, and sensation (non-motor symptoms). Individual patients' symptoms may be quite dissimilar; progression is also distinctly individual. There are four major dopamine pathways in the brain; the nigrostriatal pathway, referred to above, mediates movement and is the most conspicuously affected in early Parkinson's disease. The other pathways are the mesocortical, the mesolimbic, and the tuberoinfundibular. These pathways are associated with, respectively: volition and emotional responsiveness; desire, initiative, and reward; and sensory processes and maternal behavior. Reduction in dopamine along the non-striatal pathways is the likely explanation for much of the neuropsychiatric pathology associated with Parkinson's disease.
2006-06-08 17:46:05
·
answer #1
·
answered by mallimalar_2000 7
·
3⤊
0⤋
Parkinson's disease occurs when an section of the brain the produces dopamine deteriorates. Dopamine is one of the chemicals that involved in sending messages around the nervous system.
Each person with Parkinson's develops different symptoms. However, some of the common ones people develop early on are: shaking, muscles stiffening, episodes where a part of your body freezes up.
In the middle part of the disease people may start to have problems with walking and balance.
Toward the end of the disease anything that requires the brain to send a signal to the body to move can get pretty challenging. People have a hard time talking, swallowing, and controlling their ability to go to the bathroom.
Other symptoms that often appear during the battle with Parkinson's can be found in these blogs:
http://myparkinsonsinfo.com/index.php?p=217
http://myparkinsonsinfo.com/index.php?p=208
Especially this one:
http://myparkinsonsinfo.com/index.php?p=164
2006-06-12 15:02:12
·
answer #2
·
answered by Matt-Health 2
·
0⤊
0⤋
Eventually Parkinson's will render its patient immobile. The tremours will grow to be a constant thing. Muscle spasms will cause patient to be unable to walk around without fear of collapsing.
Incontinence will happen and inability to control one's movement as far as feeding, bathing, dressing etc. Eventually patient will be bedridden, fed through a tube and require constant nursing care.
It is considered a terminal disease, but people usually die from accidents resulting from Parkinson's symptoms such as falls(broken bones), accidents(walking around or wandering out of supervision) or infection(pnemonia etc from being unable to swallow properly and aspiring liquids into lungs which develop into pnemonia.
2006-06-10 16:58:09
·
answer #3
·
answered by tazgirl469 3
·
0⤊
0⤋
it causes your body to shake uncontrollably, mostly your hands
2006-06-09 00:34:56
·
answer #4
·
answered by blondeeboi 2
·
0⤊
0⤋
http://www.ninds.nih.gov/disorders/parkinsons_disease/parkinsons_disease.htm
2006-06-09 00:41:33
·
answer #5
·
answered by Amy 5
·
0⤊
0⤋