polyuria + polydypsia r common in IDDM, but wouldn't GLYCOSURIA be 2?

Question

all the literature i can find says GLYCOSURIA is common in NIDDM. Furthermore, y does the Polyuria happen?

IDDM = Type 1 Diabetes, NIDDM = Type 2 Diabetes, 4 the pilgrims! now try reading it slowly with me

Answer 1

Glycosuria is common in both, but depends on the level. At a plasma glucose up to about 240 mg/dL (give or take a few), the Kidney reclaims all the glucose, so above that, the glucose spills into the urine and drags water with it. In IDDM, glucose easily goes above 240, but in NIDDM, it is possible that the glucose is only slightly elevated, such that glycosuria (and even polyuria) may not happen. This is why NIDDM has more complications at diagnosis - the glucose has been elevated long enough to cause DAMAGE, but not high enough to cause SYMPTOMS. In IDDM, the sugar rises high enough to cause symptoms, and quick enough to diagnose and treat BEFORE complications.

Make sense?

Answer 2

for the polyuria, the excess glucose in plasma changes osmotic pressure between tissues and bloodstream, therefore making you hypervolemic. this amounts to a higher compensatory glomerular filtraiton rate= more excretion. glucose passing the barrier is also known to drag water (like Na).

as far as i can remember there'd be glycosuria in both cases, but more prominent in DMII

Answer 3

I do not know what you are talking about. Maybe next time you
can write a little neater........