Can anyone tell me if taking Klonopin in high dose can affect on lowering serotonin level?
Or does it increase the serotonin level?
Thanks!
2007-12-28 06:18:08 · 3 answers · asked by davegesprek 1 in Health ➔ Men's Health
Clonazepam appears to also have a secondary effect on the neurotransmitter serotonin.[9] It has shown itself to be highly effective as a short-term (3 weeks) adjunct to SSRI treatment in obsessive-compulsive disorder and clinical depression in reducing SSRI side effects with the combination being superior to SSRI treatment alone in a study funded by the manufacturers of clonazepam, Hoffman LaRoche Inc.
SSRIs increase the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor. They have varying degrees of selectivity for the other monoamine transporters, having little binding affinity for the noradrenaline and dopamine transporters.
2007-12-28 06:24:26 · answer #1 · answered by redxslash 3 · 0⤊ 1⤋
klonopin clonazepam blocks serotonin and increases is re uptake. It causes depression and makes its much worse in patients like myself . If I could go back I would not have taken it but had no choice.
2016-12-11 13:05:03 · answer #2 · answered by Ed 1 · 0⤊ 0⤋
You should really read up on Klonopin. Stevie Nicks was addicted to it and says it almost killed her. Other celebrities have said similar things about it. I don't think I'd be doing Klonopin from what I've read about it!!!!!!!!! Google it.
2007-12-28 07:56:36 · answer #3 · answered by freak 2 · 1⤊ 0⤋