proteins are initially digested in the ___________ by pepsin enzyme?

Answer 1

Proteins are subjected to the digestive action of pepsin which is secreted by the chief cells of the gastric glands lining the gastric pit of the stomach. Pepsin is at first produced as propepsin which gets activated by the Hcl secreted by the oxynctic cells of the stomach lining. The digestion of proteins by pepsin in not complete as it is an endopeptidase.

Answer 2

Gastric secretions include pepsinogen, gastric lipase, hydrochloric acid, intrinsic factor,mucus and gastrin. The cells that secrete some of these products, called gland cells are specifically known as chief cells, parietal cells and mucous neck cells. Chief cells secrete pepsinogen, the precursor to the proteolytic enzyme pepsin, and gastric lipase, which breaks down short chain triglycerides. Pepsin is secreted in an inactive form so that it does not digest proteins in the actual chief cells that secrete it; this enzyme is activated when it comes into contact with hydrochloric acid or other pepsin molecules. Parietal cells secrete hydrochloric acid via proton pumps and chloride leakage channels on their apical membranes. Apart from activating pepsinogen, this acid also kills microbes and denatures proteins. Mucous neck cells and surface cells secrete mucus, which forms a protective barrier that prevents the stomach wall from being digested by the stomach’s powerful enzymes. Gastrin is secreted by G cells, which are endocrine cells.

Answer 3

Stomach.

Pepsin is a digestive protease released by the chief cells in the stomach that functions to degrade food proteins into peptides.

Answer 4

stomach.