whats the movie called when a cartoon drawer undergoes chemotherapy and then turns into "lobo"?

Question

he had cancer and then in his late 30's he gets hooked up by his sister an erotic novel writer, with a journal writer and then loses weight and wears a fat buddha necklace to win her heart...pretending to be a motorcycle rider who likes being by himself and makes her fall inlove with him although she has a relationship with another man who ends up cheating on her....

Answer 1

...add the fact that in his new guise, he maintains a faux Austrailian or New Zealand accent, and it sounds like you're talking about the 1990 comedy, "The Boyfriend School", released theatrically as "Don't Tell Her It's Me", starring Steve Gutenburg, Kyle McLachlan, Shelley Long and Jami Gertz...